DSIP (Delta Sleep-Inducing Peptide) 10mg
Delta sleep-inducing peptide (DSIP) is a naturally occurring neuropeptide first isolated from the cerebral venous blood of rabbits during electrically induced sleep in 1977 by Schoenenberger and Monnier. This nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) crosses the blood-brain barrier and has been investigated for its role in modulating slow-wave sleep architecture, stress response, and neuroendocrine regulation. It is also studied in nociceptive-signaling and opioid-withdrawal neuroadaptation models. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Discreet, unmarked packaging
- Third-party tested to a 99%+ purity standard
Mechanism of Action
The precise receptor target of DSIP remains under investigation. Research suggests DSIP modulates GABAergic and glutamatergic neurotransmission, interacts with the hypothalamic-pituitary-adrenal (HPA) axis to reduce cortisol and ACTH levels, and may influence circadian rhythm regulation through effects on melatonin and serotonin pathways. It has also been shown to modulate delta-wave EEG activity, the characteristic oscillation pattern of deep (stage N3) sleep.
Properties
Molecular Formula
C₃₅H₄₈N₁₀O₁₅
Molecular Weight
848.81 Da
Sequence
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Half-Life
~7-8 minutes (rapid peripheral degradation)
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- Independently tested by accredited third-party laboratories.
- Held to a 99%+ purity standard.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Batch test records are published to each product as they are completed.
Research Applications
References & Citations
(2)Characterization of a delta-electroencephalogram (-sleep)-inducing peptide
Schoenenberger GA, Monnier M.
Delta sleep-inducing peptide (DSIP): a still unresolved riddle
Kovalzon VM, Strekalova TV.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.