Semaglutide 10mg
Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist: a 31-amino-acid analog of human GLP-1(7-37) bearing a C-18 fatty-diacid chain linked via a spacer to Lys26, which confers high albumin-binding affinity and resistance to DPP-4 degradation. This structural modification extends its in-vitro half-life to approximately 7 days. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Discreet, unmarked packaging
- Third-party tested to a 99%+ purity standard
Mechanism of Action
Semaglutide is an agonist of the GLP-1 receptor, a class B G-protein-coupled receptor expressed in pancreatic beta cells, gastrointestinal tissue, and the central nervous system. In research models, receptor activation is studied in the context of insulinotropic signaling, glucagon signaling, gastric-motility pathways, and hypothalamic feeding circuits. Reported preclinical endpoints include hepatic lipid-handling, cardiovascular inflammation, and neuroinflammatory signaling markers.
Properties
Molecular Formula
C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight
4113.58 Da
Sequence
His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18 diacid-γGlu-OEG-OEG)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly
Half-Life
~7 days (albumin-bound)
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 30 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- Independently tested by accredited third-party laboratories.
- Held to a 99%+ purity standard.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Batch test records are published to each product as they are completed.
Research Applications
References & Citations
(2)Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes (SUSTAIN-6)
Marso SP, Bain SC, Consoli A, et al.
A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis
Newsome PN, Buchholtz K, Cusi K, et al.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.