Semaglutide 10mg
Semaglutide is an acylated analog of human GLP-1 with Aib8 and Arg34 substitutions and derivatization at Lys26. Its receptor affinity and albumin binding were characterized in the discovery study by Lau et al. (2015). The reported mini-pig plasma pharmacokinetics do not establish an in-vitro half-life. This listing contains 10mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
Strength
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- Reported measurements · lot SEM-20260811-01Bioviridian Inc. · COA7919: purity 99.78%; content 10.34 mg.
- Stock-solution arithmetic — Semaglutide concentration calculator
Batch Tracking
Batch #
SEM-20260811-01
Tested
2026-08-23
Purity
99.78%
Method
RP-HPLC (214 nm)
Mechanism of Action
Semaglutide is a GLP-1 receptor agonist. Lau et al. (2015) characterized receptor affinity and albumin binding while optimizing acylated GLP-1 analogs. Semaglutide contains Aib8 and Arg34 substitutions and a Lys26-linked substituent; the study reported increased albumin affinity relative to liraglutide.
Properties
CAS Number
910463-68-2
Molecular Formula
C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight
4113.64 Da
Sequence
His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18 diacid-γGlu-OEG-OEG)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly
Half-Life
In-vitro half-life not established by the cited discovery study
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 30 days.
Shipping & Delivery
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Quality & Testing
- Independently tested by Bioviridian Inc. — identity by LC-MS/MS, purity by RP-HPLC (214 nm).
- Reported measurements on lot SEM-20260811-01:Bioviridian Inc. · COA7919: purity 99.78%; content 10.34 mg.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Research Applications
References & Citations
(1)Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide
Lau J, Bloch P, Schäffer L, et al.
Other strengths
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.