BPC-157
10mg
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a partial sequence of human gastric juice protein BPC. The 15-amino acid sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) has demonstrated remarkable stability in gastric acid, distinguishing it from most peptides. BPC-157 has been one of the most extensively studied peptides in preclinical tissue repair research, with over 100 published studies spanning tendon, ligament, muscle, bone, gastrointestinal, and neurological injury models.
Pricing
Mechanism of Action
BPC-157 modulates the nitric oxide (NO) system, upregulates growth factor expression including VEGF, FGF-2, and EGF receptor pathways, and promotes angiogenesis in injured tissue. It activates the FAK-paxillin pathway involved in cell migration and wound closure, and influences the GH-IGF-1 axis locally in damaged tissue. BPC-157 also interacts with the dopaminergic system, demonstrating protective effects against dopamine-depleting agents, and modulates serotonin, GABA, and opioid neurotransmitter systems.
Properties
Molecular Formula
C₆₂H₉₈N₁₆O₂₂
Molecular Weight
1419.53 Da
Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Half-Life
~4 hours (stable in gastric conditions)
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.
Research Applications
References & Citations
(3)BPC 157 and blood vessels
Seiwerth S, Brcic L, Vuletic LB, et al.
Stable gastric pentadecapeptide BPC 157-NO-system relation
Sikiric P, Seiwerth S, Rucman R, et al.
The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
Chang CH, Tsai WC, Lin MS, et al.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.