PT-141 (Bremelanotide) 10mg
Bremelanotide (PT-141) is a cyclic heptapeptide melanocortin receptor agonist derived from Melanotan-II but with selective MC4R activity. It is studied as a centrally-acting melanocortin ligand, distinct from dopaminergic and serotonergic agents, and is used to probe hypothalamic and limbic MC4R arousal-circuit signaling. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Discreet, unmarked packaging
- Third-party tested to a 99%+ purity standard
Mechanism of Action
PT-141 selectively activates MC3R and MC4R in hypothalamic and limbic structures. In research models, MC4R activation in the paraventricular nucleus and medial preoptic area is studied for oxytocinergic and dopaminergic signaling within arousal circuitry. Unlike PDE5 inhibitors, which act peripherally on vascular smooth muscle, bremelanotide engages central motivational circuitry — the basis for its use as a receptor-pharmacology tool compound.
Properties
Molecular Formula
C₅₀H₆₈N₁₄O₁₀
Molecular Weight
1025.17 Da
Sequence
Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Half-Life
~2.7 hours
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 21 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- Independently tested by accredited third-party laboratories.
- Held to a 99%+ purity standard.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Batch test records are published to each product as they are completed.
Research Applications
References & Citations
(2)The Female Sexual Response and the Melanocortin System
Kingsberg SA, Clayton AH, Pfaus JG.
Bremelanotide for female sexual dysfunctions in premenopausal women: a randomized, placebo-controlled dose-finding trial
Clayton AH, Althof SE, Kingsberg S, et al.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.