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Catalog/Retatrutide
Retatrutide
#1004
Lyophilized Peptide

Retatrutide 15mg

Retatrutide (LY3437943) is a peptide agonist of the GIP, GLP-1 and glucagon receptors. Structural and receptor-mutagenesis research examines how the same peptide engages all three receptors. This listing contains 15mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (15mg)$99.99

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1
= $99.99
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  • Free Priority shipping on US orders over $100
  • Ships same day on orders before 2 PM MST
  • Plain, secure packaging
  • Third-party tested — lot RET-20260811-02 at 99.68% purity

Batch Tracking

Batch #

RET-20260811-02

Tested

2026-08-23

Purity

99.68%

Method

RP-HPLC (214 nm)

View Certificate of Analysis
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Mechanism of Action

Retatrutide is a triple agonist at GLP-1R, GIPR and the glucagon receptor (GCGR). Li et al. (2024) determined cryo-EM structures of retatrutide bound to each receptor in complex with Gs and examined receptor mutations using cAMP signaling assays. The study identifies shared and receptor-specific peptide contacts in these experimental systems.

Properties

CAS Number

2381089-83-2

Half-Life

Not established

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 30 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
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Quality & Testing

  • Independently tested by Bioviridian Inc. — identity by LC-MS/MS, purity by RP-HPLC (214 nm).
  • Measured at 99.68% purity on lot RET-20260811-02.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.
Lot RET-20260811-02 · 99.68% purity · certificate COA7918

Research Applications

1Triple-receptor complex structural analysis
2Receptor-mutagenesis and cAMP signaling assays
3Comparative incretin and glucagon receptor pharmacology

References & Citations

(1)
1

Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide

Li W, Zhou Q, Cong Z, et al.

Cell Discov (2024)PMID: 39019866 DOI

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.

Research reference

A published identity, mechanism, and bibliography record corresponds to this catalog entry.

Research reference: Retatrutide