Retatrutide 40mg
Retatrutide (LY3437943) is a peptide agonist of the GIP, GLP-1 and glucagon receptors. Structural and receptor-mutagenesis research examines how the same peptide engages all three receptors. This listing contains 40mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Plain, secure packaging
- Certificates published per tested lot — see current coverage
- Stock-solution arithmetic — Retatrutide concentration calculator
Mechanism of Action
Retatrutide is a triple agonist at GLP-1R, GIPR and the glucagon receptor (GCGR). Li et al. (2024) determined cryo-EM structures of retatrutide bound to each receptor in complex with Gs and examined receptor mutations using cAMP signaling assays. The study identifies shared and receptor-specific peptide contacts in these experimental systems.
Properties
CAS Number
2381089-83-2
Half-Life
Not established
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 30 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- No third-party certificate has been published for this compound yet.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Certificates are published for each lot we have tested — see the 14 published so far.
Research Applications
References & Citations
(1)Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide
Li W, Zhou Q, Cong Z, et al.
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Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.