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Catalog/Ipamorelin
Ipamorelin
#1021
Lyophilized Peptide

Ipamorelin 10mg

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) and selective ghrelin/GHS receptor (GHSR) agonist. Distinguished from earlier GHS peptides (GHRP-6, GHRP-2, hexarelin) by its high selectivity for GH release without significant effects on ACTH, cortisol, prolactin, or aldosterone at GH-stimulating doses. This selectivity makes ipamorelin the cleanest GHS available for research applications requiring isolated GH-axis stimulation without confounding neuroendocrine effects. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (10mg)$59.99

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Mechanism of Action

Ipamorelin binds the ghrelin receptor (GHS-R1a) on pituitary somatotrophs, activating Gq/11-coupled phospholipase C and IP3-mediated intracellular calcium release.

Properties

CAS Number

170851-70-4

Molecular Formula

C₃₈H₄₉N₉O₅

Molecular Weight

711.85 Da

Sequence

Aib-His-D-2-Nal-D-Phe-Lys-NH₂

Half-Life

~2 hours (human, IV infusion)

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
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Quality & Testing

  • No third-party certificate has been published for this compound yet.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.

Certificates are published for each lot we have tested — see the 14 published so far.

Research Applications

1Selective GH secretagogue pharmacology studies
2GH pulse amplitude modulation without ACTH/cortisol interference
3GHRH and GHS combination study design
4Bone repair and osteoblast-proliferation models
5Gastric motility and gut function studies

References & Citations

(2)
1

Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers.

Gobburu JV, Agersø H, Jusko WJ, Ynddal L

Pharm Res (1999)PMID: 10496658 DOI
2

Ipamorelin, the first selective growth hormone secretagogue

Raun K, Hansen BS, Johansen NL, et al.

Eur J Endocrinol (1998)PMID: 9849822 DOI

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.

Research reference

A published identity, mechanism, and bibliography record corresponds to this catalog entry.

Research reference: Ipamorelin

More references from the Research Library (5)

Further papers cited in the Library's Ipamorelin record, each checked against PubMed. They describe the compound in research settings and are not statements about this product. See the full record for its identity, structure and complete bibliography.

  1. Highly potent growth hormone secretagogues: hybrids of NN703 and ipamorelin.

    Hansen TK, Ankersen M, Raun K, et al.

    Bioorganic & medicinal chemistry letters (2001)In vitro · AnimalPMID 11459660
  2. Ghrelin and glucose homeostasis.

    Delhanty PJ, van der Lely AJ

    Peptides (2011)Review articlePMID 21396419
  3. Growth hormone secretagogue receptor family members and ligands.

    Smith RG, Leonard R, Bailey AR, et al.

    Endocrine (2001)Review articlePMID 11322507
  4. Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.

    Shiimura Y, Horita S, Hamamoto A, et al.

    Nature communications (2020)In vitroPMID 32814772
  5. Determination of growth hormone releasing peptides (GHRP) and their major metabolites in human urine for doping controls by means of liquid chromatography mass spectrometry.

    Thomas A, Höppner S, Geyer H, et al.

    Analytical and bioanalytical chemistry (2011)In vitroPMID 21298258