Ipamorelin 10mg
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) and selective ghrelin/GHS receptor (GHSR) agonist. Distinguished from earlier GHS peptides (GHRP-6, GHRP-2, hexarelin) by its high selectivity for GH release without significant effects on ACTH, cortisol, prolactin, or aldosterone at GH-stimulating doses. This selectivity makes ipamorelin the cleanest GHS available for research applications requiring isolated GH-axis stimulation without confounding neuroendocrine effects. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Discreet, unmarked packaging
- Third-party tested to a 99%+ purity standard
Mechanism of Action
Ipamorelin binds the ghrelin receptor (GHS-R1a) on pituitary somatotrophs, activating Gq/11-coupled phospholipase C and IP3-mediated intracellular calcium release. This synergizes with endogenous GHRH signaling to amplify GH pulse amplitude. Ipamorelin does not suppress somatostatin release (unlike GHRH) and has minimal affinity for GHS-R1a splice variants associated with cortisol and prolactin release, explaining its superior endocrine selectivity profile.
Properties
Molecular Formula
C₃₈H₄₉N₉O₅
Molecular Weight
711.85 Da
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Half-Life
~2 hours
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- Independently tested by accredited third-party laboratories.
- Held to a 99%+ purity standard.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Batch test records are published to each product as they are completed.
Research Applications
References & Citations
(2)Ipamorelin, the first selective growth hormone secretagogue
Raun K, Hansen BS, Johansen NL, et al.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.