Matrixyl (Palmitoyl Pentapeptide-4)
10mg
Matrixyl (palmitoyl pentapeptide-4, pal-KTTKS) is a lipidated matrikine consisting of the pentapeptide Lys-Thr-Thr-Lys-Ser (KTTKS) — a subfragment of the type I procollagen C-terminal propeptide — conjugated to palmitic acid to improve lipophilicity and membrane permeability. KTTKS is a feedback fragment released during collagen processing that signals extracellular-matrix production in fibroblast models. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Discreet, unmarked packaging
- Third-party tested to a 99%+ purity standard
Mechanism of Action
The KTTKS sequence (procollagen residues 212-216) is the minimal fragment that stimulates production of type I collagen, type III collagen, and fibronectin in mesenchymal cells, acting as a matrikine in the feedback regulation of extracellular-matrix synthesis. Palmitoylation increases the peptide's lipophilicity for cell-membrane association without altering the KTTKS signaling motif. Research on this compound is largely dermatological/cosmetic-science in origin.
Properties
Molecular Formula
C₃₉H₇₅N₇O₉
Molecular Weight
774.06 Da
Sequence
Palmitoyl-Lys-Thr-Thr-Lys-Ser
Storage
Store lyophilized at -20°C protected from light. Reconstituted at 2-8°C, use within 14 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- Independently tested by accredited third-party laboratories.
- Held to a 99%+ purity standard.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Batch test records are published to each product as they are completed.
Research Applications
References & Citations
(2)A pentapeptide from type I procollagen promotes extracellular matrix production
Katayama K, Armendariz-Borunda J, Raghow R, et al.
The Effects of a Novel Series of KTTKS Analogues on Cytotoxicity and Proteolytic Activity
Tałałaj U, Uścinowicz P, Bruzgo I, et al.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.