Pinealon 20mg
Pinealon is the synthetic tripeptide Glu-Asp-Arg (EDR), one of the short peptide bioregulators developed in the Russian research tradition associated with Khavinson and colleagues. It was derived from the polypeptide preparation Cortexin. Nearly all of the published work on it comes from that one research group, largely in rat models and cultured cerebellar granule cells, and has not been widely replicated elsewhere. This listing contains 20mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Ships same day on orders before 2 PM MST
- Plain, secure packaging
- Certificates published per tested lot — see current coverage
Mechanism of Action
Khavinson and colleagues report that EDR restricts reactive oxygen species accumulation in cerebellar granule cells, neutrophils and PC12 cells under oxidative stress, and alters the time course of ERK 1/2 activation. Khavinson et al. (2020) propose direct interaction with DNA as the basis for the gene-expression effects. That proposed mechanism is the group's own hypothesis rather than an independently established one.
Properties
CAS Number
175175-23-2
Molecular Formula
C15H26N6O8
Molecular Weight
418.40 Da
Sequence
Glu-Asp-Arg
Half-Life
Not established
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- No third-party certificate has been published for this compound yet.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Certificates are published for each lot we have tested — see the 14 published so far.
Research Applications
References & Citations
(2)EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease
Khavinson V, Linkova N, Kozhevnikova E, Trofimova S.
Pinealon protects the rat offspring from prenatal hyperhomocysteinemia
Arutjunyan A, Kozina L, Stvolinskiy S, et al.
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.