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Catalog/Thymalin
Thymalin
#1078
Lyophilized Peptide

Thymalin 10mg

Thymalin is a polypeptide complex extracted from the thymus, developed in the Russian peptide-bioregulator research tradition associated with Morozov and Khavinson. It is an extract rather than a single defined sequence, so it has no single molecular formula or registry number; Linkova et al. (2023) identified the dipeptides Lys-Glu (KE) and Glu-Trp (EW) as active components. Nearly all of the published work comes from that one research group. This listing contains 10mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (10mg)$49.99

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Quantity

1
= $49.99
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  • Ships same day on orders before 2 PM MST
  • Plain, secure packaging
  • Certificates published per tested lot — see current coverage

Mechanism of Action

Khavinson et al. (2020) exposed human cord-blood hematopoietic stem cells to thymalin and reported reduced CD44 and CD117 expression with increased CD28 expression, which they interpret as stimulated differentiation toward mature T lymphocytes. Linkova et al. (2023) reported that thymalin and its KE and EW dipeptides reduced IL-1β, IL-6 and TNF-α release from LPS-stimulated human peripheral blood mononuclear cells, and proposed DNA binding by the dipeptides from molecular docking. Both mechanisms are the authors' own interpretations and have not been independently replicated.

Properties

Half-Life

Not established

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
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Quality & Testing

  • No third-party certificate has been published for this compound yet.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.

Certificates are published for each lot we have tested — see the 14 published so far.

Research Applications

1Hematopoietic stem cell differentiation assays
2Cytokine release in LPS-stimulated mononuclear cell culture
3T-lymphocyte surface marker studies
4Comparative work with its KE and EW dipeptide components

References & Citations

(2)
1

Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells

Khavinson VK, Linkova NS, Kvetnoy IM, et al.

Bull Exp Biol Med (2020)PMID: 33237528 DOI
2

The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19

Linkova N, Khavinson V, Diatlova A, et al.

Int J Mol Sci (2023)PMID: 37686182 DOI

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.