N-Acetyl Semax Amidate 30mg
N-Acetyl Semax Amidate is a doubly end-modified analog of Semax — the heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) built on the ACTH(4-7) fragment with a Pro-Gly-Pro tail in place of residues 8-10 — bearing N-terminal acetylation and C-terminal amidation. The cited studies examined unmodified Semax; they do not establish preservation of its biological activity in this doubly modified form. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Ships same day on orders before 2 PM MST
- Plain, secure packaging
- Certificates published per tested lot — see current coverage
- Stock-solution arithmetic — N-Acetyl Semax Amidate concentration calculator
Mechanism of Action
Dolotov et al. studied BDNF and TrkB expression in rat hippocampus using unmodified Semax. Manchenko et al. studied learning and pain sensitivity in rats using unmodified Semax. Neither cited study establishes a mechanism for N-Acetyl Semax Amidate. The N-terminal acetyl and C-terminal amide groups cap the peptide termini, a common strategy to slow exopeptidase cleavage; comparative stability versus unmodified Semax is itself a research endpoint.
Properties
Molecular Formula
C₃₉H₅₄N₁₀O₁₀S
Molecular Weight
854.97 Da
Sequence
Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
Half-Life
Not established
Storage
Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- No third-party certificate has been published for this compound yet.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Certificates are published for each lot we have tested — see the 14 published so far.
Research Applications
References & Citations
(2)Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
Dolotov OV, Karpenko EA, Inozemtseva LS, et al.
[Nootropic and analgesic effects of Semax following different routes of administration]
Manchenko DM, Glazova NIu, Levitskaia NG, et al.
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Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.