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Catalog/N-Acetyl Selank Amidate
N-Acetyl Selank Amidate
#1046
Lyophilized Peptide

N-Acetyl Selank Amidate

30mg

N-Acetyl Selank Amidate is a doubly end-modified analog of Selank — the heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) combining the tuftsin tetrapeptide with a Pro-Gly-Pro stabilizing sequence — bearing N-terminal acetylation and C-terminal amidation. These terminal caps are intended to increase resistance to exopeptidase degradation relative to unmodified Selank while retaining the parent peptide's GABAergic and immunomodulatory research profile. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (30mg)$67.90

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  • Ships same day on orders before 2 PM MST
  • Discreet, unmarked packaging
  • Third-party tested to a 99%+ purity standard

Mechanism of Action

As a Selank analog, it is studied for the parent peptide's mechanisms: enhancement of GABA-A receptor sensitivity without direct benzodiazepine-site binding, modulation of enkephalin metabolism (inhibition of enkephalin-degrading enzymes), and tuftsin-related immunomodulatory activity. The N-terminal acetyl and C-terminal amide groups cap the termini to slow exopeptidase cleavage; comparative stability versus unmodified Selank is itself a research endpoint.

Properties

Half-Life

~extended vs. Selank (terminal-capped; preclinical)

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
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Quality & Testing

  • Independently tested by accredited third-party laboratories.
  • Held to a 99%+ purity standard.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.

Batch test records are published to each product as they are completed.

Research Applications

1GABAergic modulation and anxiolytic-mechanism studies
2Terminal-modification peptide-stability comparisons vs. Selank
3Enkephalin-system and opioidergic interaction research
4Tuftsin-related immunomodulation studies
5Exopeptidase-resistance and half-life characterization

References & Citations

(2)
1

The optimizing action of the synthetic peptide Selank on a conditioned active avoidance reflex in rats

Kozlovskii II, Danchev ND.

Neurosci Behav Physiol (2003)PMID: 14552529 DOI
2

[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia]

Zozulia AA, Neznamov GG, Siuniakov TS, et al.

Zh Nevrol Psikhiatr Im S S Korsakova (2008)PMID: 18454096

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.