Molecular mechanism

CD36 scavenger receptor

A multifunctional scavenger receptor, distinct from the growth hormone secretagogue receptor, reported as a binding target for certain synthetic secretagogue peptides. It is recorded separately here precisely because collapsing it into the ghrelin-receptor mechanism would erase the finding that these compounds are not pharmacologically interchangeable.

Type: receptorPublished: 2026-09-13Literature/identifier verification: 2026-09-13

See this target on the receptor map

CD36FATSR-B2

Neutral molecular overview

Target identifiers

Gene symbols: CD36

Related compounds

Compound

Examorelin (Hexarelin)

Examorelin, widely supplied as hexarelin, is a synthetic hexapeptide growth hormone secretagogue carrying a 2-methylated D-tryptophan.

Compound

Pralmorelin (GHRP-2)

Pralmorelin is a synthetic hexapeptide growth hormone secretagogue acting at the ghrelin receptor, containing three D-configured residues and a naphthylalanine substitution.

Related mechanisms

receptor

Growth hormone secretagogue receptor

A G-protein-coupled receptor distinct from the GHRH receptor. Antagonist profiling reported that ipamorelin releases growth hormone through a GHRP-like receptor rather than through the GHRH receptor, establishing the two pathways as separate.

Verified bibliography

Reference 1
CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart.
Bodart V, Febbraio M, Demers A, McNicoll N, Pohankova P, Perreault A, Sejlitz T, Escher E, Silverstein RL, Lamontagne D, Ong H
Circulation research · 2002-05-03 · Journal Article
current
PMID 11988484 DOI 10.1161/01.res.0000016164.02525.b4 Examorelin (Hexarelin)CD36
Reference 2
Identification of the growth hormone-releasing peptide binding site in CD36: a photoaffinity cross-linking study.
Demers A, McNicoll N, Febbraio M, Servant M, Marleau S, Silverstein R, Ong H
The Biochemical journal · 2004-09-01 · Journal Article
current
PMID 15176951 PMC1133797 DOI 10.1042/bj20040036 Pralmorelin (GHRP-2)Examorelin (Hexarelin)CD36

Study models of these references

What kind of experiment each cited paper reports, taken from its abstract unless marked. Not a summary of results.

Reference	Study models
Bodart V et al. 2002	Study models reported: in vitro · from the abstract
Demers A et al. 2004	Study models reported: in vitro · from the abstract

Related glossary terms

Agonist Ligand G-protein-coupled receptor