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Catalog/GHK-CU
GHK-CU
#1066
Lyophilized Peptide

GHK-CU 50mg

This 50mg vial is the half-size GHK-Cu listing, alongside the 100mg. GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. Plasma GHK levels decline from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60. Originally identified by Dr. Loren Pickart in 1973 as a factor in human plasma that promoted hepatocyte function, GHK has since been shown to influence the expression of over 4,000 human genes in gene array studies. This listing contains 50mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (50mg)$34.99

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1
= $34.99
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Mechanism of Action

GHK-Cu chelates copper(II) ions with high affinity, delivering bioavailable copper to tissues where it is required for enzymatic activity (lysyl oxidase, superoxide dismutase, cytochrome c oxidase). The peptide activates tissue-repair cascades including collagen I/III synthesis, glycosaminoglycan accumulation, and decorin expression. Zhou et al. (2017) studied GHK and TGF-β1/Smad signaling in mice with bleomycin-induced lung injury.

Properties

CAS Number

89030-95-5

Molecular Formula

C14H22CuN6O4

Molecular Weight

401.91 Da

Sequence

Gly-His-Lys:Cu²⁺

Half-Life

Not established

Storage

Store lyophilized at -20°C protected from light. Reconstituted at 2-8°C, use within 7 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Full shipping details

Quality & Testing

  • No third-party certificate has been published for this compound yet.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.

Certificates are published for each lot we have tested — see the 14 published so far.

Research Applications

1Tissue-repair and collagen-remodeling studies
2Gene-expression profiling studies
3Skin aging, photoaging, and dermal matrix research
4Copper-dependent enzyme activity studies

References & Citations

(4)
1

GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition

Zhou XM, Wang GL, Wang XB, et al.

Front Pharmacol (2017)PMID: 29311918 DOI
2

GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration

Pickart L, Vasquez-Soltero JM, Margolina A.

BioMed Res Int (2015)PMID: 26236730 DOI
3

GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes

Pickart L, Vasquez-Soltero JM, Margolina A.

Cosmetics (2015)DOI
4

The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice

Park JR, Lee H, Kim SI, Yang SR.

Oncotarget (2016)PMID: 27517151

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.