HCG (Human Chorionic Gonadotropin) 5,000 IU
Human chorionic gonadotropin (HCG), supplied as a 5,000 IU lyophilized vial, a smaller presentation than the 10,000 IU vial. HCG is a glycoprotein hormone consisting of an alpha subunit (common to LH, FSH, TSH) and a unique beta subunit that confers biological specificity. HCG mimics luteinizing hormone (LH) activity by binding the LH/CG receptor on Leydig cells and ovarian theca cells. It is a non-covalent heterodimer of a 92-residue alpha subunit (UniProt P01215, shared with LH, FSH and TSH) and a 145-residue beta subunit (UniProt P0DN86) that confers its identity; no single molecular formula can be assigned, because eight glycosylation sites carry carbohydrate that varies between preparations (~30% of mass; unglycosylated backbone ~25,700 Da). It has a significantly longer half-life than LH due to its greater degree of glycosylation, making it a durable LH-receptor agonist for research applications requiring sustained Leydig cell or theca cell stimulation. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
Strength
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2+ save 5% · 5+ save 10% · 10+ save 20%
- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Plain, secure packaging
- Certificates published per tested lot — see current coverage
- Stock-solution arithmetic — HCG concentration calculator
Mechanism of Action
HCG binds the LH/CG receptor (LHCGR), a Gs-coupled GPCR on testicular Leydig cells, activating cAMP/PKA signaling that stimulates steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme (CYP11A1), thereby driving de novo testosterone biosynthesis. In ovarian tissue, HCG triggers final oocyte maturation, ovulation, and corpus luteum formation.
Properties
CAS Number
9002-61-3
Molecular Weight
~36,700 Da
Half-Life
~36 h terminal (human serum)
Storage
Store lyophilized at 2-8°C. Reconstituted at 2-8°C, use within 30 days.
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- No third-party certificate has been published for this compound yet.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Certificates are published for each lot we have tested — see the 14 published so far.
Research Applications
References & Citations
(2)Metabolic and renal clearance rates of purified human chorionic gonadotropin.
Wehmann RE, Nisula BC
Biological functions of hCG and hCG-related molecules
Cole LA.
Other strengths
Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.