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Catalog/KLOW
KLOW
#1042
Lyophilized Peptide

KLOW 80mg

KLOW is a proprietary four-component peptide blend combining GHK-Cu (50mg), TB-500 (10mg), BPC-157 (10mg), and KPV (10mg) in a single 80mg lyophilized vial. Its components are individually studied in tissue-repair and inflammatory-signaling research models. The cited papers concern individual compounds, not this combination; they do not establish complementary activity or synergy for the blend. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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  • Reported measurements · lot KLW-20260828-01Bioviridian Inc. · COA8896: purity 99.75%; content 10.44, 50.21, 10.61, 10.39 mg.
  • Stock-solution arithmetic — KLOW concentration calculator

Batch Tracking

Batch #

KLW-20260828-01

Tested

2026-09-08

Purity

99.75%

Method

RP-HPLC (214 nm)

View Certificate of Analysis
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Mechanism of Action

The cited evidence concerns individual compounds. Pickart et al. review increased collagen synthesis with GHK-Cu in rat wound models; this does not establish an effect of this blend. TB-500 is a short peptide fragment derived from the parent peptide thymosin beta-4; the thymosin beta-4 literature cited below characterises the parent peptide rather than the fragment. Malinda et al. studied full-length thymosin beta-4 in rat skin wounds and a keratinocyte migration assay. The BPC-157 review discusses NO-system relations in animal injury models; Chang et al. reported FAK/paxillin phosphorylation and migration in cultured rat Achilles tendon fibroblasts. Kannengiesser et al. reported KPV effects that were at least partially independent of MC1R signaling in mouse colitis. Dalmasso et al. studied KPV uptake and inflammatory signaling in human intestinal epithelial and immune cell lines. None of these cited studies tested the combined formulation.

Properties

Component CAS Numbers

KPV 67727-97-3 · GHK-Cu 89030-95-5 · BPC-157 137525-51-0 · TB-500 885340-08-9

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.

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  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
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Quality & Testing

  • Independently tested by Bioviridian Inc. — identity by LC-MS/MS, purity by RP-HPLC (214 nm).
  • Reported measurements on lot KLW-20260828-01:Bioviridian Inc. · COA8896: purity 99.75%; content 10.44, 50.21, 10.61, 10.39 mg.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.
Lot KLW-20260828-01 · certificatesBioviridian Inc. · COA8896: purity 99.75%; content 10.44, 50.21, 10.61, 10.39 mg.

Research Applications

1Review of individual-component research
2Component-specific evidence and model comparison
3Assessment of evidence gaps for the combined formulation

References & Citations

(6)
1

PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.

Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al.

Gastroenterology (2008)PMID: 18061177 DOI
2

The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.

Chang CH, Tsai WC, Lin MS, et al.

J Appl Physiol (1985) (2011)PMID: 21030672 DOI
3

GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration

Pickart L, Vasquez-Soltero JM, Margolina A.

BioMed Res Int (2015)PMID: 26236730 DOI
4

Thymosin beta4 accelerates wound healing

Malinda KM, Sidhu GS, Mani H, et al.

J Invest Dermatol (1999)PMID: 10469335 DOI
5

Stable gastric pentadecapeptide BPC 157-NO-system relation

Sikiric P, Seiwerth S, Rucman R, et al.

Curr Pharm Des (2014)PMID: 23755725 DOI
6

Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease

Kannengiesser K, Maaser C, Heidemann J, et al.

Inflamm Bowel Dis (2008)PMID: 18092346 DOI

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.

Research reference

The Library holds no record for this blend. Each component named on this listing has a published identity record; those records describe the individual compounds, not this combination.

More references from the Research Library (15)

Further papers cited in the Library's records for this blend's components, each checked against PubMed. They describe the individual compounds in research settings and are not statements about this product or this combination.

GHK-Cu (7)

From the GHK-Cu record.

  1. Structure of the Glycyl-L-histidyl-L-lysine--copper(II) complex in solution.

    Freedman JH, Pickart L, Weinstein B, et al.

    Biochemistry (1982)Chemical, structural or analytical; no biological modelPMID 6291585
  2. The interaction of copper(II) and glycyl-L-histidyl-L-lysine, a growth-modulating tripeptide from plasma.

    Lau SJ, Sarkar B

    The Biochemical journal (1981)In vitroPMID 7340824
  3. Ultrasensitive and Label-Free Detection of Copper Ions by GHK-Modified Asymmetric Nanochannels.

    An P, Zhang Z, Yang J, et al.

    Analytical chemistry (2023)Chemical, structural or analytical; no biological modelPMID 37624577
  4. Effects of glycyl-histidyl-lysyl chelated Cu(II) on ferritin dependent lipid peroxidation.

    Miller DM, DeSilva D, Pickart L, et al.

    Advances in experimental medicine and biology (1990)In vitroPMID 2244543
  5. The human tri-peptide GHK and tissue remodeling.

    Pickart L

    Journal of biomaterials science. Polymer edition (2008)Review articlePMID 18644225
  6. N.m.r. and e.p.r. investigation of the interaction of copper(II) and glycyl-L-histidyl-L-lysine, a growth-modulating tripeptide from plasma.

    Laussac JP, Haran R, Sarkar B

    The Biochemical journal (1983)Chemical, structural or analytical; no biological modelPMID 6303307
  7. SPARC is a source of copper-binding peptides that stimulate angiogenesis.

    Lane TF, Iruela-Arispe ML, Johnson RS, et al.

    The Journal of cell biology (1994)In vitro · In vivo (subject not stated)PMID 7514608

TB-500 (3)

From the TB-500 record.

  1. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential.

    Esposito S, Deventer K, Goeman J, et al.

    Drug testing and analysis (2012)Chemical, structural or analytical; no biological modelPMID 22962027
  2. Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography-mass spectrometry.

    Ho EN, Kwok WH, Lau MY, et al.

    Journal of chromatography. A (2012)In vitro · AnimalPMID 23084823
  3. TB500/TB1000 and SGF1000: A scientific approach for a better understanding of misbranded and adulterated drugs.

    Delcourt V, Garcia P, Chabot B, et al.

    Drug testing and analysis (2022)Chemical, structural or analytical; no biological modelPMID 36482504

BPC-157 (2)

From the BPC-157 record.

  1. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.

    Gwyer D, Wragg NM, Wilson SL

    Cell and tissue research (2019)Review articlePMID 30915550
  2. Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.

    Seiwerth S, Milavic M, Vukojevic J, et al.

    Frontiers in pharmacology (2021)Review articlePMID 34267654

KPV (3)

From the KPV record.

  1. Anti-inflammatory activity of alpha-MSH(11-13) analogs: influences of alteration in stereochemistry.

    Hiltz ME, Catania A, Lipton JM

    Peptides (1991)AnimalPMID 1788140
  2. The neuroimmunomodulatory peptide alpha-MSH.

    Ichiyama T, Sato S, Okada K, et al.

    Annals of the New York Academy of Sciences (2000)Review articlePMID 11268347
  3. Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides.

    Getting SJ, Schiöth HB, Perretti M

    The Journal of pharmacology and experimental therapeutics (2003)In vitro · AnimalPMID 12750433