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Catalog/Selank
Selank
#1035
Lyophilized Peptide

Selank 10mg

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) combining the tuftsin tetrapeptide (Thr-Lys-Pro-Arg) with the Pro-Gly-Pro (PGP) stabilizing sequence also used in Semax. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank is classified as an anxiolytic and nootropic peptide in Russian pharmacopoeia. It modulates GABAergic neurotransmission and has demonstrated anxiolytic-like effects comparable to benzodiazepines without sedation, motor impairment, or dependence potential in preclinical models. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (10mg)$45.00

2+ save 5% · 5+ save 10% · 10+ save 20%

Quantity

1
= $45.00
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  • Free Priority shipping on US orders over $100
  • Ships same day on orders before 2 PM MST
  • Discreet, unmarked packaging
  • Third-party tested to a 99%+ purity standard

Mechanism of Action

Selank enhances GABA-A receptor sensitivity to GABA without direct benzodiazepine site binding, increasing GABAergic inhibitory tone in limbic structures. It also modulates serotonin metabolism by inhibiting enkephalinase activity, increasing endogenous enkephalin levels. Additionally, Selank upregulates IL-6 expression, modulates T-helper cell balance (Th1/Th2), and enhances NK cell activity, indicating immunomodulatory properties. The tuftsin component is a known phagocytosis-stimulating peptide recognized by neutrophils and macrophages.

Properties

Molecular Formula

C₃₃H₅₇N₁₁O₉

Molecular Weight

751.87 Da

Sequence

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Half-Life

~3-5 minutes (peripheral)

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
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Quality & Testing

  • Independently tested by accredited third-party laboratories.
  • Held to a 99%+ purity standard.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.

Batch test records are published to each product as they are completed.

Research Applications

1Anxiolytic mechanisms without benzodiazepine site involvement
2GABAergic modulation and limbic system pharmacology
3Immunomodulation and tuftsin-related phagocytic function
4Comparative anxiolytic-like activity vs. benzodiazepines
5Cognitive performance under stress conditions

References & Citations

(2)
1

Anxiolytic action of the synthetic peptide Selank

Seredenin SB, Kozlovskii II, Blednov YA, et al.

Bull Exp Biol Med (1998)DOI
2

Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia

Zozulia AA, Neznamov GG, Siuniakov TS, et al.

Zh Nevrol Psikhiatr Im S S Korsakova (2008)PMID: 18454096

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.