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Catalog/Tirzepatide
Tirzepatide
#1002
Lyophilized Peptide

Tirzepatide 30mg

Tirzepatide is a dual agonist of the glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors: a 39-amino-acid synthetic peptide based on the native GIP sequence with modifications conferring GLP-1 receptor co-agonism. A C20 fatty-diacid moiety linked through a glutamic acid and two mini-PEG spacers enhances albumin binding and in-vitro stability. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (30mg)$100.00

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  • Ships same day on orders before 2 PM MST
  • Discreet, unmarked packaging
  • Third-party tested to a 99%+ purity standard

Mechanism of Action

Tirzepatide engages both the GIP receptor (GIPR) and the GLP-1 receptor (GLP-1R) with a bias toward GIPR (~5:1). In research models, GIPR activation in adipose tissue is studied for lipid storage and adipokine signaling, and central GIPR signaling for feeding-circuit pathways; the combined receptor engagement is used to study insulinotropic, glucagon, and energy-metabolism signaling relative to selective GLP-1R agonism.

Properties

Molecular Formula

C₂₂₅H₃₄₈N₄₈O₆₈

Molecular Weight

4813.45 Da

Half-Life

~5 days

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 30 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
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Quality & Testing

  • Independently tested by accredited third-party laboratories.
  • Held to a 99%+ purity standard.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.

Batch test records are published to each product as they are completed.

Research Applications

1Dual incretin-receptor signaling analysis
2Comparative pharmacology vs. selective GLP-1 agonists
3Adipose-tissue biology and lipid-pathway research
4Beta-cell function models
5Receptor co-agonism and comorbidity models

References & Citations

(5)
1

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (SURPASS-2)

Frías JP, Davies MJ, Rosenstock J, et al.

N Engl J Med (2021)PMID: 34170647 DOI
2

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

Coskun T, Sloop KW, Loghin C, et al.

Mol Metab (2018)PMID: 30473097 DOI
3

Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist

Willard FS, Douros JD, Gabe MB, et al.

JCI Insight (2020)PMID: 32730231 DOI
4

Structural determinants of dual incretin receptor agonism by tirzepatide

Sun B, Willard FS, Feng D, et al.

Proc Natl Acad Sci USA (2022)PMID: 35333651 DOI
5

GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice (animal study)

Samms RJ, Christe ME, Collins KA, et al.

J Clin Invest (2021)PMID: 34003802 DOI

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Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.