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Research Catalog

same family

Ipamorelin vs GHRP-6

Ipamorelin and GHRP-6 are separate members of the growth-hormone secretagogue class. Their recorded peptide compositions differ.

Published: 2026-10-03Library record comparison: 2026-10-03

01

Identity side by side

Recorded molecular identities of Ipamorelin and GHRP-6
Recorded fieldIpamorelinGHRP-6
Canonical nameIpamorelinGHRP-6
Aliasesnot recordedHexapeptide-2; Growth hormone-releasing peptide-6
Development codesNNC 26-0161not recorded
CAS170851-70-487616-84-0
UNIIY9M3S784Z64H7N4I6X6A
PubChem CID98316599919153
Molecular formulaC38H49N9O5C46H56N12O6
Molecular weight (Da)711.9873
Sequence length (residues)5not recorded
Terminal modificationsC-terminal amideC-terminal amide
Structural modificationsAlpha-aminoisobutyric acid (Aib) at position 1; D-2-naphthylalanine at position 3; D-phenylalanine at position 4not recorded

Ipamorelin: nomenclature notes

Identified within a series of compounds lacking the central Ala-Trp dipeptide of growth hormone-releasing peptide-1. PubChem lists NNC 26-0161 as a development identifier.

GHRP-6: nomenclature notes

GHRP-6 is a hexapeptide with a C-terminal amide. A separate PubChem record for the same formula and mass carries a synonym belonging to GHRP-2, a different peptide; identity should be established against CAS 87616-84-0 rather than by name matching alone.

02

Recorded modification details

An aligned one-letter sequence is not recorded for this pair. The stored modification and sequence notes are shown below.

Ipamorelin

Terminal modifications
C-terminal amide
Structural modifications
Alpha-aminoisobutyric acid (Aib) at position 1; D-2-naphthylalanine at position 3; D-phenylalanine at position 4
Stored three-letter notation
Aib · His · D-2-Nal · D-Phe · Lys
Sequence notes
Pentapeptide Aib-His-D-2-Nal-D-Phe-Lys-NH2. Contains alpha-aminoisobutyric acid, D-2-naphthylalanine, and D-phenylalanine, so a standard one-letter representation does not apply. The sequence is stated identically in the PubChem synonym record and in the original characterization paper.

GHRP-6

Terminal modifications
C-terminal amide
Structural modifications
not recorded

03

Recorded mechanisms

These lists show the links recorded in each monograph. An unlisted link does not establish its absence from the molecule’s biology.

Recorded only for Ipamorelin

not recorded

Recorded only for GHRP-6

not recorded

04

Recorded compound classes

Shared recorded links

Recorded only for Ipamorelin

not recorded

Recorded only for GHRP-6

not recorded

05

References for the relationship

  1. Ipamorelin, the first selective growth hormone secretagogue.

    Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH

    European journal of endocrinology · 1998-11 · Journal Article

    current
    PMID 9849822DOI 10.1530/eje.0.1390552IpamorelinGHRP-6GHS-R1a
  2. Growth hormone secretagogue receptor family members and ligands.

    Smith RG, Leonard R, Bailey AR, Palyha O, Feighner S, Tan C, Mckee KK, Pong SS, Griffin P, Howard A

    Endocrine · 2001-02 · Review

    current
    PMID 11322507DOI 10.1385/ENDO:14:1:009GHRP-6IpamorelinGHS-R1a

06

Read the full monographs

Ipamorelin →GHRP-6 →