Peptide Sequence Comparisons

parent and analog

Cagrilintide is an acylated amylin analog with residue substitutions. The two records share a disulfide-linked peptide scaffold but describe distinct molecules.

Aligned residue sequences and modification notes

parent and analog

Pramlintide differs from the recorded human amylin sequence at three positions, carrying proline in place of Ala25, Ser28 and Ser29.

Aligned residue sequences and modification notes

commonly confused

GHK is the free tripeptide; GHK-Cu is a copper coordination species. Their molecular identities and registry numbers are distinct.

Identity and modification records

parent and analog

PT-141 is the C-terminal free-acid form of the Melanotan II scaffold. The recorded cyclic scaffold is shared, while the terminal group differs.

Identity and modification records

commonly confused

These records distinguish the substituted non-DAC backbone recorded as CJC-1295 from sermorelin’s GRF(1-29) sequence. The cited CJC report concerns DAC-bearing conjugates; its species must not be conflated with this non-DAC record.

Aligned residue sequences and modification notes

same family

The stored sermorelin sequence matches the first 29 residues of tesamorelin’s 44-residue GRF backbone. Their chain lengths and recorded terminal features differ.

Aligned residue sequences and modification notes

same family

Semaglutide and liraglutide are distinct acylated GLP-1 analogs. The Library records separate molecular identities for them.

Identity and modification records

parent and analog

GLP-1(7-37) is the recorded structural reference for semaglutide. Semaglutide carries residue substitutions and a derivatized lysine side chain.

Identity and modification records

same family

Ipamorelin and GHRP-6 are separate members of the growth-hormone secretagogue class. Their recorded peptide compositions differ.

Identity and modification records

fragment of

The complete glucagon residue sequence forms the N-terminal portion of oxyntomodulin. Oxyntomodulin has an additional eight-residue C-terminal extension.

Aligned residue sequences and modification notes

same family

These are distinct GLP-1 processing forms: one ends in an amidated arginine, while the other retains an additional C-terminal glycine.

Aligned residue sequences and modification notes

fragment of

Kisspeptin-10 matches the final ten residues of kisspeptin-14. This sequence relationship does not establish a serial processing pathway.

Aligned residue sequences and modification notes

commonly confused

Melanotan I is a linear thirteen-residue analog, while Melanotan II is a cyclic lactam heptapeptide. The shared name does not identify the same molecule.

Identity and modification records

parent and analog

Pal-GHK is the N-palmitoylated derivative of the GHK tripeptide. Covalent acylation distinguishes it from free GHK.

Identity and modification records

parent and analog

The Matrixyl record describes N-palmitoylated KTTKS. The unmodified KTTKS peptide has a separate molecular identity.

Identity and modification records

parent and analog

HNG is the single-substitution humanin analog with glycine in place of serine at residue 14. The recorded sequences otherwise match.

Aligned residue sequences and modification notes

same family

Tirzepatide and retatrutide are distinct members of the Library’s multi-receptor incretin analog class, with separate development codes and molecular identities.

Identity and modification records

same family

Survodutide and mazdutide are distinct peptide analogs with different main-chain sequences, conjugation positions, linkers and lipids.

Identity and modification records

parent and analog

These records share the seven-residue Selank sequence. The amidate record specifies additional N-terminal acetyl and C-terminal amide groups.

Aligned residue sequences and modification notes

parent and analog

These records share the seven-residue Semax sequence. The amidate record specifies additional N-terminal acetyl and C-terminal amide groups.

Aligned residue sequences and modification notes