Molecular mechanism
Corticotropin-releasing factor receptor 1
CRFR1 is a class B G-protein-coupled receptor. Independent receptor-expression and receptor-complex studies identify binding of the human/rat-sequence corticotropin-releasing factor peptide.
See this target on the receptor map
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Neutral molecular overview
CRFR1 is a class B G-protein-coupled receptor. Independent receptor-expression and receptor-complex studies identify binding of the human/rat-sequence corticotropin-releasing factor peptide.
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Target identifiers
- Gene symbols
- CRHR1
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Related compounds
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Related mechanisms
No related mechanism is declared in this seed record.
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Verified bibliography
Reference 1
Expression cloning of a human corticotropin-releasing-factor receptor.Chen R, Lewis KA, Perrin MH, Vale WW
Proceedings of the National Academy of Sciences of the United States of America · 1993-10-01 · Journal Article
currentReference 2
Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.Liang YL, Belousoff MJ, Zhao P, Koole C, Fletcher MM, Truong TT, Julita V, Christopoulos G, Xu HE, Zhang Y, Khoshouei M, Christopoulos A, Danev R, Sexton PM, Wootten D
Molecular cell · 2020-01-30 · Journal Article
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Study models of these references
What kind of experiment each cited paper reports, taken from its abstract unless marked. Not a summary of results.
| Reference | Study models |
|---|---|
| Chen R et al. 1993 | Study models reported: in vitro · from the abstract |
| Liang YL et al. 2020 | Study models reported: in vitro · from the abstract |
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Related glossary terms
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Related Purely Peptides research articles
No existing Research Article is mapped to this mechanism seed record.