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Molecular mechanism

Focal adhesion kinase signaling

A cytoskeletal signaling pathway in which focal adhesion kinase and paxillin phosphorylation coordinate cell adhesion, spreading, and migration.

Type: signaling-pathwayPublished: 2026-09-04Literature/identifier verification: 2026-08-23

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FAK-paxillin pathwayFAK signaling

01

Neutral molecular overview

A cytoskeletal signaling pathway in which focal adhesion kinase and paxillin phosphorylation coordinate cell adhesion, spreading, and migration.

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Target identifiers

Gene symbols
PTK2, PXN

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Related compounds

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Related mechanisms

No related mechanism is declared in this seed record.

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Verified bibliography

  1. Reference 1

    The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.

    Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH

    Journal of applied physiology (Bethesda, Md. : 1985) · 2010-10-28 · Journal Article

    current
  2. Reference 2

    current
  3. Reference 3

    Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.

    Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, Pavlov KH, Petrovic A, Sikiric S, Vranes H, Prtoric A, Zizek H, Durasin T, Dobric I, Staresinic M, Strbe S, Knezevic M, Sola M, Kokot A, Sever M, Lovric E, Skrtic A, Blagaic AB, Sikiric P

    Frontiers in pharmacology · 2021-06-29 · Review

    current

Study models of these references

What kind of experiment each cited paper reports, taken from its abstract unless marked. Not a summary of results.

ReferenceStudy models
Chang CH et al. 2010Study models reported: in vitro · from the abstract
Gwyer D et al. 2019Review article
Seiwerth S et al. 2021Review article

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Related glossary terms

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Related Purely Peptides research articles

No existing Research Article is mapped to this mechanism seed record.