Molecular mechanism
Integrin αIIbβ3
A heterodimeric integrin whose interaction with eptifibatide is characterized by direct structural and solution studies.
See this target on the receptor map
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Neutral molecular overview
A heterodimeric integrin whose interaction with eptifibatide is characterized by direct structural and solution studies.
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Target identifiers
No target identifier beyond the verified name and aliases is listed for this mechanism.
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Related compounds
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Related mechanisms
No related mechanism is declared in this seed record.
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Verified bibliography
Reference 1
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics.Xiao T, Takagi J, Coller BS, Wang JH, Springer TA
Nature · 2004-09-19 · Journal Article
currentReference 2
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation.Hantgan RR, Rocco M, Nagaswami C, Weisel JW
Protein science : a publication of the Protein Society · 2001-08 · Journal Article
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Study models of these references
What kind of experiment each cited paper reports, taken from its abstract unless marked. Not a summary of results.
| Reference | Study models |
|---|---|
| Xiao T et al. 2004 | Study models reported: in vitro · from the abstract |
| Hantgan RR et al. 2001 | Study models reported: in vitro · from the abstract |
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Related glossary terms
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Related Purely Peptides research articles
No existing Research Article is mapped to this mechanism seed record.