Retatrutide + Cagrilintide 5mg / 5mg
A single lyophilized vial containing retatrutide 5mg + cagrilintide 5mg (1:1), 10mg total. Retatrutide (LY3437943) is an agonist at GIP, GLP-1 and glucagon receptors; cagrilintide (AM833) is a lipidated amylin analogue studied at amylin and calcitonin receptors. The cited papers concern the individual components, not this combination; they do not establish an effect of the blend. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.
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- Free Priority shipping on US orders over $100
- Ships same day on orders before 2 PM MST
- Plain, secure packaging
- Certificates published per tested lot — see current coverage
- Stock-solution arithmetic — Retatrutide + Cagrilintide concentration calculator
Mechanism of Action
The cited evidence concerns individual components. Li et al. (2024) examined retatrutide-bound GLP-1R, GIPR and GCGR structures and receptor-mutagenesis cAMP assays. Kruse et al. (2021) describe the development of the lipidated amylin analogue cagrilintide. Fletcher et al. (2021) compared AM833 with calcitonin-family receptor agonists using receptor binding, activation and regulation assays. No cited study tested the combined 5mg + 5mg (1:1) formulation.
Properties
Component CAS Numbers
Retatrutide 2381089-83-2 · Cagrilintide 1415456-99-3
Shipping & Delivery
- Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
- US shipping from $5. Free Priority on orders $100+ (before discounts).
- Plain, unmarked packaging — no branding or product names on the outside.
- Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Quality & Testing
- No third-party certificate has been published for this compound yet.
- USA-based; dispatched from Phoenix, Arizona.
- Supplied strictly for in-vitro laboratory research — not for human use.
Certificates are published for each lot we have tested — see the 14 published so far.
Research Applications
References & Citations
(3)Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide
Li W, Zhou Q, Cong Z, et al.
Development of Cagrilintide, a Long-Acting Amylin Analogue.
Kruse T, Hansen JL, Dahl K, et al.
AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists.
Fletcher MM, Keov P, Truong TT, et al.
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Research Use Only
This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.