Lot certificates published
Plain, secure packaging
Catalog/Semax
Semax
#1051
Lyophilized Peptide

Semax 30mg

Semax, 30mg lyophilized vial — the same synthetic heptapeptide as the 10mg listing at a larger reagent quantity. Semax (Met-Glu-His-Phe-Pro-Gly-Pro) derives from the N-terminal region of adrenocorticotropic hormone, retaining the ACTH(4-7) fragment Met-Glu-His-Phe and substituting a Pro-Gly-Pro tripeptide for residues 8-10. The larger vial mass suits extended time-course work and multi-arm protocols where a smaller vial would require repeated reconstitution. See the Semax 10mg listing for the full pharmacological profile. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

Select Option

Single (30mg)$54.99

2+ save 5% · 5+ save 10% · 10+ save 20%

Quantity

1
= $54.99
Buy now
  • Free Priority shipping on US orders over $100
  • Ships same day on orders before 2 PM MST
  • Plain, secure packaging
  • Reported measurements · lot SMX-20260828-01Bioviridian Inc. · COA8894: purity 99.78%; content 30.72 mg.
  • Stock-solution arithmetic — Semax concentration calculator

Batch Tracking

Batch #

SMX-20260828-01

Tested

2026-09-08

Purity

99.78%

Method

RP-HPLC (214 nm)

View Certificate of Analysis
Telegram - @purely_peptides orders@purelypeptides.org

Mechanism of Action

In rats, Dolotov et al. reported increased BDNF and TrkB expression in the hippocampus after a single exposure to Semax. Agapova et al. reported increased NGF gene expression in rat hippocampus but decreased NGF gene expression in rat frontal cortex after a single exposure. It modulates the melanocortin system via MC4R interaction without significant adrenal steroidogenic activity in the studied dose ranges. Additional mechanisms include modulation of serotonergic and dopaminergic neurotransmission. Identical mechanism to the Semax 10mg listing.

Properties

CAS Number

80714-61-0

Molecular Formula

C₃₇H₅₁N₉O₁₀S

Molecular Weight

813.93 Da

Sequence

Met-Glu-His-Phe-Pro-Gly-Pro

Half-Life

Not established

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
Full shipping details

Quality & Testing

  • Independently tested by Bioviridian Inc. — identity by LC-MS/MS, purity by RP-HPLC (214 nm).
  • Reported measurements on lot SMX-20260828-01:Bioviridian Inc. · COA8894: purity 99.78%; content 30.72 mg.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.
Lot SMX-20260828-01 · certificatesBioviridian Inc. · COA8894: purity 99.78%; content 30.72 mg.

Research Applications

1Region-specific BDNF/NGF expression studies in rat brain
2Ischemic neuroprotection and post-ischemic repair models
3Cognition and memory-consolidation research
4Extended time-course and repeat-sampling protocols

References & Citations

(3)
1

Neurotrophin gene expression in rat brain under the action of Semax, an analogue of ACTH 4-10.

Agapova TY, Agniullin YV, Shadrina MI, et al.

Neurosci Lett (2007)PMID: 17353092 DOI
2

[Nootropic and analgesic effects of Semax following different routes of administration]

Manchenko DM, Glazova NIu, Levitskaia NG, et al.

Ross Fiziol Zh Im I M Sechenova (2010)PMID: 21268834
3

Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus

Dolotov OV, Karpenko EA, Inozemtseva LS, et al.

Brain Res (2006)PMID: 16996037

Other strengths

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.

Research reference

A published identity, mechanism, and bibliography record corresponds to this catalog entry.

Research reference: Semax

More references from the Research Library (1)

Further papers cited in the Library's Semax record, each checked against PubMed. They describe the compound in research settings and are not statements about this product. See the full record for its identity, structure and complete bibliography.

  1. The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind.

    Vanhee C, Francotte A, Janvier S, et al.

    Drug testing and analysis (2020)Chemical, structural or analytical; no biological modelPMID 31667971