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Catalog/Tesamorelin
Tesamorelin
#1020
Lyophilized Peptide

Tesamorelin 10mg

Tesamorelin (TH9507) is a synthetic analog of human GHRH(1-44)-NH2 with a trans-3-hexenoyl moiety attached to the N-terminal Tyr1 residue. The cited preclinical study examined resistance to enzymatic deactivation, plasma degradation and GH/IGF-1 responses. This listing contains 10mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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  • Reported measurements · lot TSM-20260828-01Bioviridian Inc. · COA8893: purity 99.74%; content 10.35 mg.
  • Stock-solution arithmetic — Tesamorelin concentration calculator

Batch Tracking

Batch #

TSM-20260828-01

Tested

2026-09-08

Purity

99.74%

Method

RP-HPLC (214 nm)

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Mechanism of Action

Ferdinandi et al. (2007) characterized TH9507, the modified GHRH analog tesamorelin. Its N-terminal trans-3-hexenoyl modification conferred resistance to DPP-IV deactivation and slowed peptide degradation in rat, dog and human plasma in vitro. GH and IGF-1 responses were also measured in preclinical animal studies; those findings do not establish preservation of physiological GH pulsatility.

Properties

CAS Number

218949-48-5

Molecular Formula

C₂₂₁H₃₆₆N₇₂O₆₇S

Molecular Weight

5135.86 Da

Half-Life

~21-45 min (dog plasma)

Storage

Store lyophilized at 2-8°C. Reconstituted at 2-8°C, use within 14 days.

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  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
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Quality & Testing

  • Independently tested by Bioviridian Inc. — identity by LC-MS/MS, purity by RP-HPLC (214 nm).
  • Reported measurements on lot TSM-20260828-01:Bioviridian Inc. · COA8893: purity 99.74%; content 10.35 mg.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.
Lot TSM-20260828-01 · certificatesBioviridian Inc. · COA8893: purity 99.74%; content 10.35 mg.

Research Applications

1Plasma peptide-degradation assays
2N-terminal modification and DPP-IV resistance comparisons
3Preclinical GH and IGF-1 response characterization

References & Citations

(1)
1

Non-clinical pharmacology and safety evaluation of TH9507, a human growth hormone-releasing factor analogue

Ferdinandi ES, Brazeau P, High K, et al.

Basic Clin Pharmacol Toxicol (2007)PMID: 17214611 DOI

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.

Research reference

A published identity, mechanism, and bibliography record corresponds to this catalog entry.

Research reference: Tesamorelin

More references from the Research Library (4)

Further papers cited in the Library's Tesamorelin record, each checked against PubMed. They describe the compound in research settings and are not statements about this product. See the full record for its identity, structure and complete bibliography.

  1. Tesamorelin.

    Grunfeld C, Dritselis A, Kirkpatrick P

    Nature reviews. Drug discovery (2011)News itemPMID 21283099
  2. Tesamorelin, a human growth hormone releasing factor analogue.

    Wang Y, Tomlinson B

    Expert opinion on investigational drugs (2009)Review articlePMID 19243281
  3. Drug evaluation: tesamorelin, a synthetic human growth hormone releasing factor.

    Tomlinson B

    Current opinion in investigational drugs (London, England : 2000) (2006)Review articlePMID 17086939
  4. Population pharmacokinetic analysis of tesamorelin in HIV-infected patients and healthy subjects.

    González-Sales M, Barrière O, Tremblay PO, et al.

    Clinical pharmacokinetics (2015)Human participants (interventional)PMID 25358450