parent and analog
These records share the seven-residue Selank sequence. The amidate record specifies additional N-terminal acetyl and C-terminal amide groups.
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| Recorded field | Selank | N-Acetyl Selank Amidate |
|---|---|---|
| Canonical name | Selank | N-Acetyl Selank Amidate |
| Aliases | Selanc; Tuftsin-Pro-Gly-Pro; TP-7 | not recorded |
| Development codes | TP-7 | not recorded |
| CAS | 129954-34-3 | not recorded |
| UNII | TS9JR8EP1G | not recorded |
| PubChem CID | 11765600 | not recorded |
| Molecular formula | C33H57N11O9 | C35H60N12O9 |
| Molecular weight (Da) | 751.9 | 792.9 |
| Sequence length (residues) | 7 | 7 |
| Terminal modifications | not recorded | N-terminal acetylation at Thr1; C-terminal amide at Pro7 |
| Structural modifications | not recorded | not recorded |
Selank is the tetrapeptide tuftsin (Thr-Lys-Pro-Arg) extended at the C-terminus with Pro-Gly-Pro. The catalog separately lists N-acetyl selank amidate, a distinct molecule carrying an N-terminal acetyl group and a C-terminal amide. Registry numbers reported for that modified variant are inconsistent across suppliers and no CAS for it is published here.
The complete name specifies both terminal groups. A bare N-acetyl Selank label does not specify the C-terminal group and is not an alias here. Acetate salt terminology does not establish covalent N-acetylation. PubChem CID 133082488 and UNII J3PM702O93 describe the N-acetyl Selank free acid, C35H59N11O10, and are not identifiers for this amidate. No CAS, PubChem CID or UNII is assigned here because no matching authoritative record was verified.
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Positions are numbered from each stored sequence’s first residue. Highlighted cells differ or extend beyond the other chain; a dash indicates no aligned residue. One-letter notation does not encode terminal groups or stereochemistry. Read the recorded notes below.
| Selank | 1T | 2K | 3P | 4R | 5P | 6G | 7P |
|---|---|---|---|---|---|---|---|
| N-Acetyl Selank Amidate | 1T | 2K | 3P | 4R | 5P | 6G | 7P |
The stored one-letter residue sequences match at every position. Recorded terminal and structural features remain separate identity fields.
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These lists show the links recorded in each monograph. An unlisted link does not establish its absence from the molecule’s biology.
not recorded
not recorded
not recorded
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not recorded
not recorded
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Vanhee C, Francotte A, Janvier S, Deconinck E
Drug testing and analysis · 2020-01-29 · Journal Article
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