Molecular mechanism
Kisspeptin receptor
KISS1R is a G-protein-coupled receptor historically reported as GPR54 and AXOR12. Foundational records identify KISS1-derived peptides as its endogenous ligands.
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Neutral molecular overview
KISS1R is a G-protein-coupled receptor historically reported as GPR54 and AXOR12. Foundational records identify KISS1-derived peptides as its endogenous ligands.
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Target identifiers
No target identifier beyond the verified name and aliases is declared in this Phase 1A record.
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Related compounds
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Related mechanisms
No related mechanism is declared in this seed record.
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Verified bibliography
- Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor.current
Ohtaki T, Shintani Y, Honda S, Matsumoto H, Hori A, Kanehashi K, Terao Y, Kumano S, Takatsu Y, Masuda Y, Ishibashi Y, Watanabe T, Asada M, Yamada T, Suenaga M, Kitada C, Usuki S, Kurokawa T, Onda H, Nishimura O, Fujino M
Nature · 2001-05-31 · Journal Article
- The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.current
Kotani M, Detheux M, Vandenbogaerde A, Communi D, Vanderwinden JM, Le Poul E, Brézillon S, Tyldesley R, Suarez-Huerta N, Vandeput F, Blanpain C, Schiffmann SN, Vassart G, Parmentier M
The Journal of biological chemistry · 2001-07-16 · Journal Article
- AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.current
Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC
The Journal of biological chemistry · 2001-05-31 · Journal Article
- current
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Related glossary terms
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Related Purely Peptides research articles
No existing Research Article is mapped to this mechanism seed record.