GnRH peptide analogs

Compound

Cetrorelix

Cetrorelix is a synthetic linear decapeptide with defined D/L configuration and nonstandard residues, an acetylated N terminus and an amidated C terminus. This record describes the parent without counterion.

cetrorelixum

Compound

Degarelix

Degarelix is a synthetic linear decapeptide with an acetylated N terminus, an amidated C terminus and explicitly configured nonstandard residues. This record describes the parent without acetate or hydrate components.

Degarelixum

Compound

Leuprolide (leuprorelin)

Leuprorelin, also called leuprolide, is a synthetic nine-residue peptide with an L-pyroglutamyl residue at position 1, D-leucine at position 6 and an N-ethylamide on the C-terminal proline. This record describes the parent peptide without counterion or hydrate.

Leuprolide · Leuprorelinum

Compound

Triptorelin

Triptorelin is a synthetic ten-residue peptide with an L-pyroglutamyl residue at position 1, D-tryptophan at position 6 and a C-terminal glycinamide. This record describes the parent peptide without counterion.

Triptorelinum

receptor

GnRH receptor

The GnRH receptor is a G-protein-coupled receptor encoded in humans by GNRHR. The records linked here cite direct binding measurements for synthetic peptide analogs, made at the human receptor or, where stated, at the rat receptor expressed in cultured cells.