Compound monograph
Angiotensin II (Ile5, free peptide)
Angiotensin II is a linear octapeptide composed of eight L-amino-acid residues. This record describes the Ile5 free peptide with unmodified amino and carboxyl termini.
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Identity & nomenclature
Angiotensin II is a linear octapeptide composed of eight L-amino-acid residues. This record describes the Ile5 free peptide with unmodified amino and carboxyl termini.
The record fixes Ile at position 5 and excludes counterion-containing and substituted species. CAS is withheld because the dossier did not complete the required issuer qualification.
Canonical name: Angiotensin II.
Declared aliases and development codes: AII, AngII.
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Molecular properties
| Molecular formula | C50H71N13O12 |
|---|---|
| Molecular mass | 1046.197 Da |
| PubChem CID | 172198 |
| UNII | M089EFU921 |
| One-letter sequence | DRVYIHPF |
| Three-letter sequence | Asp–Arg–Val–Tyr–Ile–His–Pro–Phe |
| Terminal groups | Free N-terminus; Free C-terminal carboxyl |
Positions count the mature chain from 1. All chiral amino-acid residues are L; glycine is achiral. Terminal groups are recorded separately.
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Structural characteristics
The chain contains standard L-amino-acid residues and no inter-residue covalent closure.
Terminal features: Free N-terminus, Free C-terminal carboxyl.
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Molecular targets & mechanisms
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Analytical considerations
The molecular formula describes the parent; the average mass is calculated using CIAAW 2024 abridged atomic weights.
What the studies reported
No verified findings are published for this record under Content Policy v1.
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Verified bibliography
Cited studies by type
The one paper this record cites, counted by the kind of work each reports. A count is the size of this record's selection, not of the research that exists, and says nothing about results, safety, effectiveness or approval.
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Reference 1
On the molecular basis of the recognition of angiotensin II (AII). NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131.Tzakos AG, Bonvin AM, Troganis A, Cordopatis P, Amzel ML, Gerothanassis IP, van Nuland NA
European journal of biochemistry · 2003-03 · Journal Article
current
Study models of these references
What kind of experiment each cited paper reports, taken from its abstract unless marked. Not a summary of results.
| Reference | Study models |
|---|---|
| Tzakos AG et al. 2003 | Chemical, structural or analytical study; no biological model reported |
Record history
Published 2026-10-21.
No changes to this record's content have been recorded since publication.
Each entry names the parts of this record that changed on that date. Changes to links between records and to catalogue links are not listed. This history covers the tracked record fields; study findings are not listed here.
Cite this record: Purely Peptides Research Library. Angiotensin II (Ile5, free peptide). Published 2026-10-21. https://purelypeptides.org/research/compounds/angiotensin-ii/
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Methodology & citation verification
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