Source provenance
Verified Bibliography
A library-wide index of source records whose PubMed identifiers, DOI metadata, and titles have local verification receipts.
278 sources
Study-model labels say what kind of experiment a paper reports, taken from its abstract unless marked. They say nothing about its results and may not list every method in the paper. The filters select references in this Library by the kind of work they report; they do not rank compounds or sources, and the Library cites a selection of the literature, not all of it. Filtered views can be shared by copying the page address.
Reference 1
Efficacy and safety of mazdutide in adults with obesity or overweight: a US-based, multicentre, phase 2, randomised, placebo-controlled clinical trial.Hsia SH, Bays HE, Billings LK, Weideman AMK, Mather KJ, Coskun T, Haupt A, Thomas MK, Tham LS, Calderon B, Ni W, De Araujo OFG
The lancet. Diabetes & endocrinology · 2026-08-21 · Journal Article
currentReference 2
Goldilocks-Inspired Design of Mid-Size Macrocycles for Selective Targeting of Human Melanocortin Receptors.Merlino F, Jia L, Boccino I, Carotenuto A, Tammaro F, Santoro F, Thompson PE, Grieco P
Journal of medicinal chemistry · 2026-08-13 · Journal Article
currentReference 3
Molecular Mechanisms of Islet Amyloid Polypeptide Aggregation: Towards Chemical Strategies to Prevent Amyloid Formation and to Design Non-Aggregating Peptide Therapeutics.Bousch C, Bérubé F, Babych M, Ongeri S, Bourgault S
International journal of molecular sciences · 2026-03-12 · Review
currentReference 4
Halide-Mediated Electrochemical Peptide Synthesis Applicable to Highly Sterically Hindered Amino Acids.Shinjo-Nagahara S, Hiratsuka G, Okada Y, Kitano Y, Chiba K
Organic letters · 2026-02-05 · Journal Article
currentReference 5
Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3.Carvas AO, Leuthardt A, Kulka P, Lommi G, Hassan S, Coester B, Lundh S, Pers T, Secher A, Raun K, Lutz TA, Le Foll C
EBioMedicine · 2025-07-03 · Journal Article
currentReference 6
Design and Development of an Organocatalyst for Light Accelerated Amide and Peptide Synthesis.Li Y, Li J, Shen Z, Kuang H, Zuo Q, Bao G, Ni J, Sun W, Wang R
ACS central science · 2025-06-30 · Journal Article
currentReference 7
Molecular recognition of two approved drugs Macimorelin and Anamorelin by the growth hormone secretagogue receptor.Wang RL, Sun J, Liu H, Guo SM, Zhang Y, Hu W, Wang J, Liu H, Zhuang YW, Jiang Y, Xie X, Xu HE, Wang Y
Acta pharmacologica Sinica · 2025-06-20 · Journal Article
currentReference 8
Synthesis of Diastereomerically Pure Cetrorelix Acetate by Using Fmoc Solid-Phase Peptide Synthesis (SPPS) Strategy: A Commercially Viable Approach.Aluri K, Basavoju S, Rangisetty JB, Pullagurla MR, Pitta BR
Journal of peptide science : an official publication of the European Peptide Society · 2025-06 · Journal Article
currentReference 9
Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS.Becker JO, Shijo SK, Huynh HH, Forrest KL, MacCoss MJ, Emrick MA, Goonatilleke E, Hoofnagle AN
Journal of mass spectrometry and advances in the clinical lab · 2025-04-11 · Journal Article
currentReference 10
Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors.Cao J, Belousoff MJ, Johnson RM, Keov P, Mariam Z, Deganutti G, Christopoulos G, Hick CA, Reedtz-Runge S, Glendorf T, Ballarín-González B, Raun K, Bayly-Jones C, Wootten D, Sexton PM
Nature communications · 2025-04-10 · Journal Article
currentReference 11
Glucose-dependent insulinotropic polypeptide (GIP).Müller TD, Adriaenssens A, Ahrén B, Blüher M, Birkenfeld AL, Campbell JE, Coghlan MP, D'Alessio D, Deacon CF, DelPrato S, Douros JD, Drucker DJ, Figueredo Burgos NS, Flatt PR, Finan B, Gimeno RE, Gribble FM, Hayes MR, Hölscher C, Holst JJ, Knerr PJ, Knop FK, Kusminski CM, Liskiewicz A, Mabilleau G, Mowery SA, Nauck MA, Novikoff A, Reimann F, Roberts AG, Rosenkilde MM, Samms RJ, Scherer PE, Seeley RJ, Sloop KW, Wolfrum C, Wootten D, DiMarchi RD, Tschöp MH
Molecular metabolism · 2025-02-28 · Review
currentReference 12
The structure and function of the ghrelin receptor coding for drug actions.Shiimura Y, Im D, Tany R, Asada H, Kise R, Kurumiya E, Wakasugi-Masuho H, Yasuda S, Matsui K, Kishikawa JI, Kato T, Murata T, Kojima M, Iwata S, Masuho I
Nature structural & molecular biology · 2025-01-20 · Journal Article
currentReference 13
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron.Sloop KW, Cox AL, Wainscott DB, White A, Droz BA, Stutsman C, Showalter AD, Suter TM, Dunbar JD, Snider BM, O'Farrell LS, Hewitt N, Ruble JC, Padgett LR, Woerly EM, Peterson JA, Coskun T, Liu Z, Coutant DE, Ai M, Emmerson PJ, Sangwung P, Willard FS
Science translational medicine · 2024-12-18 · Journal Article
currentReference 14
Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder.Mottolese N, Loi M, Trazzi S, Tassinari M, Uguagliati B, Candini G, Iqbal K, Medici G, Ciani E
Journal of neurodevelopmental disorders · 2024-11-26 · Journal Article
currentReference 15
Carbocyclic setmelanotide analogs maintain biochemical potency at melanocortin 4 receptors.Gary S, Roy A, Bloom S
Journal of peptide science : an official publication of the European Peptide Society · 2024-10-12 · Journal Article
currentReference 16
Physicochemical and structural analysis of N-phenylacetyl-L-prolylglycine ethyl ester (Noopept) - An active pharmaceutical ingredient with nootropic activity.Araj SK, Szeleszczuk Ł, Gubica T, Zielińska-Pisklak M, Bethanis K, Christoforides E, Dudek MK, Pisklak DM
Journal of pharmaceutical and biomedical analysis · 2024-09-16 · Journal Article
currentReference 17
In vitro pharmacological characterization of growth hormone secretagogue receptor ligands using the dynamic mass redistribution and calcium mobilization assays.Sturaro C, Ruzza C, Ferrari F, Pola P, Argentieri M, Frezza A, Marzola E, Bettegazzi B, Cattaneo S, Pietra C, Malfacini D, Calò G
European journal of pharmacology · 2024-08-10 · Journal Article
currentReference 18
Investigating the detection of the novel doping‐relevant peptide kisspeptin‐10 in urine using liquid chromatography high‐resolution mass spectrometry.Colpaert T, Risseeuw M, Deventer K, Van Eenoo P
Biomedical chromatography : BMC · 2024-07-08 · Journal Article
currentReference 19
Structural basis for hormone recognition and distinctive Gq protein coupling by the kisspeptin receptor.Shen S, Wang D, Liu H, He X, Cao Y, Chen J, Li S, Cheng X, Xu HE, Duan J
Cell reports · 2024-06-26 · Journal Article
currentReference 20
Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial.Sanyal AJ, Kaplan LM, Frias JP, Brouwers B, Wu Q, Thomas MK, Harris C, Schloot NC, Du Y, Mather KJ, Haupt A, Hartman ML
Nature medicine · 2024-06-10 · Clinical Trial, Phase II
currentReference 21
Harnessing the melanocortin system in the control of food intake and glucose homeostasis.Swan P, Johnson B, le Roux CW, Miras AD
Peptides · 2024-06-02 · Review
currentReference 22
Spexin Diminishes Atrial Fibrillation Vulnerability by Acting on Galanin Receptor 2.Li D, Liu Y, Li C, Zhou Z, Gao K, Bao H, Yang J, Xue G, Yin D, Zhao X, Shen K, Zhang L, Li J, Li C, Song J, Zhao L, Pei Y, Xuan L, Zhang Y, Lu Y, Zhang ZR, Yang B, Li Y, Pan Z
Circulation · 2024-05-10 · Journal Article
currentReference 23
The dual GCGR/GLP-1R agonist survodutide: Biomarkers and pharmacological profiling for clinical candidate selection.Thomas L, Martel E, Rist W, Uphues I, Hamprecht D, Neubauer H, Augustin R
Diabetes, obesity & metabolism · 2024-04-01 · Journal Article
currentReference 24
A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease.Kim SJ, Miller B, Hartel NG, Ramirez R 2nd, Braniff RG, Leelaprachakul N, Huang A, Wang Y, Arpawong TE, Crimmins EM, Wang P, Sun X, Liu C, Levy D, Yen K, Petzinger GM, Graham NA, Jakowec MW, Cohen P
Molecular psychiatry · 2024-01-03 · Journal Article
currentReference 25
A Biomimetic C-Terminal Extension Strategy for Photocaging Amidated Neuropeptides.Layden AE, Ma X, Johnson CA, He XJ, Buczynski SA, Banghart MR
Journal of the American Chemical Society · 2023-08-31 · Journal Article
currentReference 26
Evidence of natural selection in the mitochondrial-derived peptides humanin and SHLP6.Gruschus JM, Morris DL, Tjandra N
Scientific reports · 2023-08-29 · Journal Article
currentReference 27
Ultrasensitive and Label-Free Detection of Copper Ions by GHK-Modified Asymmetric Nanochannels.An P, Zhang Z, Yang J, Wang T, Wang Z, Sun CL, Qin C, Li J
Analytical chemistry · 2023-08-25 · Journal Article
currentReference 28
Structural analysis of the dual agonism at GLP-1R and GCGR.Li Y, Zhou Q, Dai A, Zhao F, Chang R, Ying T, Wu B, Yang D, Wang MW, Cong Z
Proceedings of the National Academy of Sciences of the United States of America · 2023-08-07 · Journal Article
currentReference 29
Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.Horváth D, Dürvanger Z, K Menyhárd D, Sulyok-Eiler M, Bencs F, Gyulai G, Horváth P, Taricska N, Perczel A
Nature communications · 2023-08-01 · Journal Article
currentReference 30
Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons.Kim SK, Tran LT, NamKoong C, Choi HJ, Chun HJ, Lee YH, Cheon M, Chung C, Hwang J, Lim HH, Shin DM, Choi YH, Kim KW
Nature communications · 2023-07-19 · Journal Article
currentReference 31
Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA.Rosenstock J, Frias J, Jastreboff AM, Du Y, Lou J, Gurbuz S, Thomas MK, Hartman ML, Haupt A, Milicevic Z, Coskun T
Lancet (London, England) · 2023-06-26 · Clinical Trial, Phase II
currentReference 32
Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.Jastreboff AM, Kaplan LM, Frías JP, Wu Q, Du Y, Gurbuz S, Coskun T, Haupt A, Milicevic Z, Hartman ML, Retatrutide Phase 2 Obesity Trial Investigators
The New England journal of medicine · 2023-06-26 · Clinical Trial, Phase II
currentReference 33
A New Regioselective Synthesis of the Cysteine-Rich Peptide Linaclotide.Qiu Z, Dai X, Fan C, Cao Y, Lv Z, Liang X, Meng F
Molecules (Basel, Switzerland) · 2023-01-19 · Journal Article
currentReference 34
Structural basis of signaling regulation of the human melanocortin-2 receptor by MRAP1.Luo P, Feng W, Ma S, Dai A, Wu K, Chen X, Yuan Q, Cai X, Yang D, Wang MW, Eric Xu H, Jiang Y
Cell research · 2023-01-02 · Journal Article
currentReference 35
TB500/TB1000 and SGF1000: A scientific approach for a better understanding of misbranded and adulterated drugs.Delcourt V, Garcia P, Chabot B, Barnabé A, Bouscarel M, Loup B, Popot MA, Bailly-Chouriberry L
Drug testing and analysis · 2022-12-23 · Journal Article
currentReference 36
The G protein-coupled receptor ligand apelin-13 ameliorates skeletal muscle atrophy induced by chronic kidney disease.Enoki Y, Nagai T, Hamamura Y, Osa S, Nakamura H, Taguchi K, Watanabe H, Maruyama T, Matsumoto K
Journal of cachexia, sarcopenia and muscle · 2022-12-23 · Journal Article
currentReference 37
BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy.Zimmermann T, Thomas L, Baader-Pagler T, Haebel P, Simon E, Reindl W, Bajrami B, Rist W, Uphues I, Drucker DJ, Klein H, Santhanam R, Hamprecht D, Neubauer H, Augustin R
Molecular metabolism · 2022-11-07 · Journal Article
currentReference 38
Molecular basis for the activation of thyrotropin-releasing hormone receptor.Ji SY, Dong YJ, Chen LN, Zang SK, Wang J, Shen DD, Guo J, Qin J, Zhang H, Wang WW, Shen Q, Zhang Y, Song Z, Mao C
Cell discovery · 2022-10-25 · Letter
currentReference 39
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept.Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, O'Farrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z
Cell metabolism · 2022-08-18 · Journal Article
currentReference 40
Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds.Mitchell W, Tamucci JD, Ng EL, Liu S, Birk AV, Szeto HH, May ER, Alexandrescu AT, Alder NN
eLife · 2022-08-01 · Journal Article
currentReference 41
Characterization of a new L-carnosine synthase mined from deep-sea sediment metagenome.She J, Fu L, Zheng X, Li J, Wang L, Yu B, Ju J
Microbial cell factories · 2022-06-27 · Journal Article
currentReference 42
Structural insights into human brain-gut peptide cholecystokinin receptors.Ding Y, Zhang H, Liao YY, Chen LN, Ji SY, Qin J, Mao C, Shen DD, Lin L, Wang H, Zhang Y, Li XM
Cell discovery · 2022-06-07 · Journal Article
currentReference 43
Structural insights into galanin receptor signaling.Jiang W, Zheng S
Proceedings of the National Academy of Sciences of the United States of America · 2022-05-20 · Journal Article
currentReference 44
On the Utility of Chemical Strategies to Improve Peptide Gut Stability.Kremsmayr T, Aljnabi A, Blanco-Canosa JB, Tran HNT, Emidio NB, Muttenthaler M
Journal of medicinal chemistry · 2022-04-14 · Journal Article
currentReference 45
Demonstration of a Common DPhe(7) to DNal(2')(7) Peptide Ligand Antagonist Switch for Melanocortin-3 and Melanocortin-4 Receptors Identifies the Systematic Mischaracterization of the Pharmacological Properties of Melanocortin Peptides.Gimenez LE, Noblin TA, Williams SY, Mullick Bagchi S, Ji RL, Tao YX, Jeppesen CB, Conde-Frieboes KW, Sawyer TK, Grieco P, Cone RD
Journal of medicinal chemistry · 2022-04-11 · Journal Article
currentReference 46
Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor.Xu Y, Cai H, You C, He X, Yuan Q, Jiang H, Cheng X, Jiang Y, Xu HE
Cell research · 2022-04-01 · Letter
currentReference 47
Structural determinants of dual incretin receptor agonism by tirzepatide.Sun B, Willard FS, Feng D, Alsina-Fernandez J, Chen Q, Vieth M, Ho JD, Showalter AD, Stutsman C, Ding L, Suter TM, Dunbar JD, Carpenter JW, Mohammed FA, Aihara E, Brown RA, Bueno AB, Emmerson PJ, Moyers JS, Kobilka TS, Coghlan MP, Kobilka BK, Sloop KW
Proceedings of the National Academy of Sciences of the United States of America · 2022-03-25 · Journal Article
currentReference 48
CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists.Tomassi S, Dimmito MP, Cai M, D'Aniello A, Del Bene A, Messere A, Liu Z, Zhu T, Hruby VJ, Stefanucci A, Cosconati S, Mollica A, Di Maro S
Journal of medicinal chemistry · 2022-02-21 · Journal Article
currentReference 49
Cryo-EM structures of human bradykinin receptor-G(q) proteins complexes.Shen J, Zhang D, Fu Y, Chen A, Yang X, Zhang H
Nature communications · 2022-02-07 · Journal Article
currentReference 50
Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.Heyder NA, Kleinau G, Speck D, Schmidt A, Zschunke S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, Hilger D, Schacherl M, Biebermann H, Hilal T, Kühnen P, Kobilka BK, Scheerer P
Cell research · 2021-09-24 · Journal Article
currentReference 51
Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor.Liu Q, Yang D, Zhuang Y, Croll TI, Cai X, Dai A, He X, Duan J, Yin W, Ye C, Zhou F, Wu B, Zhao Q, Xu HE, Wang MW, Jiang Y
Nature chemical biology · 2021-09-23 · Journal Article
currentReference 52
Molecular basis for kinin selectivity and activation of the human bradykinin receptors.Yin YL, Ye C, Zhou F, Wang J, Yang D, Yin W, Wang MW, Xu HE, Jiang Y
Nature structural & molecular biology · 2021-09-09 · Journal Article
currentReference 53
Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation.Di Micco S, Musella S, Sala M, Scala MC, Andrei G, Snoeck R, Bifulco G, Campiglia P, Fasano A
International journal of molecular sciences · 2021-08-30 · Journal Article
currentReference 54
Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor.Ma S, Chen Y, Dai A, Yin W, Guo J, Yang D, Zhou F, Jiang Y, Wang MW, Xu HE
Cell research · 2021-08-27 · Journal Article
currentReference 55
Structural insights into ligand recognition and activation of the melanocortin-4 receptor.Zhang H, Chen LN, Yang D, Mao C, Shen Q, Feng W, Shen DD, Dai A, Xie S, Zhou Y, Qin J, Sun JP, Scharf DH, Hou T, Zhou T, Wang MW, Zhang Y
Cell research · 2021-08-25 · Journal Article
currentReference 56
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor.Wang Y, Guo S, Zhuang Y, Yun Y, Xu P, He X, Guo J, Yin W, Xu HE, Xie X, Jiang Y
Nature communications · 2021-08-20 · Journal Article
currentReference 57
Synthesis, Physicochemical Characterization, In Vitro 2D/3D Human Cell Culture, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1-7) Peptide and PNA5 with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers.Alabsi W, Acosta MF, Al-Obeidi FA, Hay M, Polt R, Mansour HM
Pharmaceutics · 2021-08-17 · Journal Article
currentReference 58
Development of Cagrilintide, a Long-Acting Amylin Analogue.Kruse T, Hansen JL, Dahl K, Schäffer L, Sensfuss U, Poulsen C, Schlein M, Hansen AMK, Jeppesen CB, Dornonville de la Cour C, Clausen TR, Johansson E, Fulle S, Skyggebjerg RB, Raun K
Journal of medicinal chemistry · 2021-07-21 · Journal Article
currentReference 59
Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes.Zhang X, Belousoff MJ, Liang YL, Danev R, Sexton PM, Wootten D
Cell reports · 2021-07-13 · Journal Article
currentReference 60
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, Pavlov KH, Petrovic A, Sikiric S, Vranes H, Prtoric A, Zizek H, Durasin T, Dobric I, Staresinic M, Strbe S, Knezevic M, Sola M, Kokot A, Sever M, Lovric E, Skrtic A, Blagaic AB, Sikiric P
Frontiers in pharmacology · 2021-06-29 · Review
currentReference 61
Therapeutic Peptides Targeting PPI in Clinical Development: Overview, Mechanism of Action and Perspectives.Cabri W, Cantelmi P, Corbisiero D, Fantoni T, Ferrazzano L, Martelli G, Mattellone A, Tolomelli A
Frontiers in molecular biosciences · 2021-06-14 · Review
currentReference 62
Improving the Gastrointestinal Stability of Linaclotide.Braga Emidio N, Tran HNT, Andersson A, Dawson PE, Albericio F, Vetter I, Muttenthaler M
Journal of medicinal chemistry · 2021-05-12 · Journal Article
currentReference 63
Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist.Pickford P, Lucey M, Rujan RM, McGlone ER, Bitsi S, Ashford FB, Corrêa IR, Hodson DJ, Tomas A, Deganutti G, Reynolds CA, Owen BM, Tan TM, Minnion J, Jones B, Bloom SR
Molecular metabolism · 2021-04-30 · Journal Article
currentReference 64
Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.Israeli H, Degtjarik O, Fierro F, Chunilal V, Gill AK, Roth NJ, Botta J, Prabahar V, Peleg Y, Chan LF, Ben-Zvi D, McCormick PJ, Niv MY, Shalev-Benami M
Science (New York, N.Y.) · 2021-04-15 · Journal Article
currentReference 65
AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists.Fletcher MM, Keov P, Truong TT, Mennen G, Hick CA, Zhao P, Furness SGB, Kruse T, Clausen TR, Wootten D, Sexton PM
The Journal of pharmacology and experimental therapeutics · 2021-03-16 · Journal Article
currentReference 66
General synthetic strategy for regioselective ultrafast formation of disulfide bonds in peptides and proteins.Laps S, Atamleh F, Kamnesky G, Sun H, Brik A
Nature communications · 2021-02-08 · Journal Article
currentReference 67
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist.Kawai T, Sun B, Yoshino H, Feng D, Suzuki Y, Fukazawa M, Nagao S, Wainscott DB, Showalter AD, Droz BA, Kobilka TS, Coghlan MP, Willard FS, Kawabe Y, Kobilka BK, Sloop KW
Proceedings of the National Academy of Sciences of the United States of America · 2020-11-11 · Journal Article
currentReference 68
Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein.Fukuhara S, Kobayashi K, Kusakizako T, Iida W, Kato M, Shihoya W, Nureki O
Biochemical and biophysical research communications · 2020-09-30 · Journal Article
currentReference 69
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.Willard FS, Douros JD, Gabe MB, Showalter AD, Wainscott DB, Suter TM, Capozzi ME, van der Velden WJ, Stutsman C, Cardona GR, Urva S, Emmerson PJ, Holst JJ, D'Alessio DA, Coghlan MP, Rosenkilde MM, Campbell JE, Sloop KW
JCI insight · 2020-09-03 · Journal Article
currentReference 70
Palmitate differentially regulates Spexin, and its receptors Galr2 and Galr3, in GnRH neurons through mechanisms involving PKC, MAPKs, and TLR4.Wang L, Tran A, Lee J, Belsham DD
Molecular and cellular endocrinology · 2020-08-22 · Journal Article
currentReference 71
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.Shiimura Y, Horita S, Hamamoto A, Asada H, Hirata K, Tanaka M, Mori K, Uemura T, Kobayashi T, Iwata S, Kojima M
Nature communications · 2020-08-19 · Journal Article
currentReference 72
Structure and dynamics of the active Gs-coupled human secretin receptor.Dong M, Deganutti G, Piper SJ, Liang YL, Khoshouei M, Belousoff MJ, Harikumar KG, Reynolds CA, Glukhova A, Furness SGB, Christopoulos A, Danev R, Wootten D, Sexton PM, Miller LJ
Nature communications · 2020-08-18 · Journal Article
currentReference 73
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors.Darbalaei S, Yuliantie E, Dai A, Chang R, Zhao P, Yang D, Wang MW, Sexton PM, Wootten D
Biochemical pharmacology · 2020-07-17 · Journal Article
currentReference 74
In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B(2) Receptor Antagonist.Lesage A, Gibson C, Marceau F, Ambrosi HD, Saupe J, Katzer W, Loenders B, Charest-Morin X, Knolle J
Frontiers in pharmacology · 2020-06-19 · Journal Article
currentReference 75
Combining MALDI mass spectrometry imaging and droplet-base surface sampling analysis for tissue distribution, metabolite profiling, and relative quantification of cyclic peptide melanotan II.Chen B, Vavrek M, Gundersdorf R, Zhong W, Cancilla MT
Analytica chimica acta · 2020-05-24 · Journal Article
currentReference 76
Determination of the melanocortin-4 receptor structure identifies Ca(2+) as a cofactor for ligand binding.Yu J, Gimenez LE, Hernandez CC, Wu Y, Wein AH, Han GW, McClary K, Mittal SR, Burdsall K, Stauch B, Wu L, Stevens SN, Peisley A, Williams SY, Chen V, Millhauser GL, Zhao S, Cone RD, Stevens RC
Science (New York, N.Y.) · 2020-04-24 · Journal Article
currentReference 77
Stability Test of PACAP in Eye Drops.Kovacs AK, Atlasz T, Werling D, Szabo E, Reglodi D, Toth GK
Journal of molecular neuroscience : MN · 2020-04-22 · Journal Article
currentReference 78
Liquid-Phase Total Synthesis of Plecanatide Aided by Diphenylphosphinyloxyl Diphenyl Ketone (DDK) Derivatives.Li H, Chao J, Zhang Z, Tian G, Li J, Chang N, Qin C
Organic letters · 2020-04-10 · Journal Article
currentReference 79
Semaglutide lowers body weight in rodents via distributed neural pathways.Gabery S, Salinas CG, Paulsen SJ, Ahnfelt-Rønne J, Alanentalo T, Baquero AF, Buckley ST, Farkas E, Fekete C, Frederiksen KS, Helms HCC, Jeppesen JF, John LM, Pyke C, Nøhr J, Lu TT, Polex-Wolf J, Prevot V, Raun K, Simonsen L, Sun G, Szilvásy-Szabó A, Willenbrock H, Secher A, Knudsen LB, Hogendorf WFJ
JCI insight · 2020-03-26 · Journal Article
currentReference 80
Rational development of a high-affinity secretin receptor antagonist.Dong M, Harikumar KG, Raval SR, Milburn JE, Clark C, Alcala-Torano R, Mobarec JC, Reynolds CA, Ghirlanda G, Christopoulos A, Wootten D, Sexton PM, Miller LJ
Biochemical pharmacology · 2020-03-23 · Journal Article
currentReference 81
Structural basis of G(s) and G(i) recognition by the human glucagon receptor.Qiao A, Han S, Li X, Li Z, Zhao P, Dai A, Chang R, Tai L, Tan Q, Chu X, Ma L, Thorsen TS, Reedtz-Runge S, Yang D, Wang MW, Sexton PM, Wootten D, Sun F, Zhao Q, Wu B
Science (New York, N.Y.) · 2020-03-20 · Journal Article
currentReference 82
How May GIP Enhance the Therapeutic Efficacy of GLP-1?Samms RJ, Coghlan MP, Sloop KW
Trends in endocrinology and metabolism: TEM · 2020-03-16 · Review
currentReference 83
Full-length human GLP-1 receptor structure without orthosteric ligands.Wu F, Yang L, Hang K, Laursen M, Wu L, Han GW, Ren Q, Roed NK, Lin G, Hanson MA, Jiang H, Wang MW, Reedtz-Runge S, Song G, Stevens RC
Nature communications · 2020-03-09 · Journal Article
currentReference 84
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.Wingler LM, Skiba MA, McMahon C, Staus DP, Kleinhenz ALW, Suomivuori CM, Latorraca NR, Dror RO, Lefkowitz RJ, Kruse AC
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| Li H et al. 2020 | Chemical, structural or analytical study; no biological model reported |
| Gabery S et al. 2020 | Study models reported: in vitro; animal (rat, mouse) · from the full text |
| Dong M et al. 2020 | Study models reported: in vitro · from the abstract |
| Qiao A et al. 2020 | Study models reported: in vitro · from the abstract |
| Samms RJ et al. 2020 | Review article |
| Wu F et al. 2020 | Study models reported: in vitro · from the abstract |
| Wingler LM et al. 2020 | Study models reported: in vitro · from the abstract |
| Kovács P et al. 2020 | Study models reported: in vitro · from the abstract |
| Khavinson V et al. 2020 | Review article |
| Liang YL et al. 2020 | Study models reported: in vitro · from the abstract |
| Vanhee C et al. 2020 | Chemical, structural or analytical study; no biological model reported |
| Asada H et al. 2019 | Study models reported: in vitro · from the abstract |
| Wyss JC et al. 2019 | Study models reported: in vitro; animal (mouse) · from the abstract |
| Knudsen LB et al. 2019 | Review article |
| Gwyer D et al. 2019 | Review article |
| Lajin B et al. 2019 | Chemical, structural or analytical study; no biological model reported |
| Zhang X et al. 2019 | Study models reported: in vitro · from the abstract |
| Debbabi S et al. 2018 | Study models reported: in vitro · from the abstract |
| Coskun T et al. 2018 | Study models reported: in vitro; animal (mouse); human participants (interventional) · from the abstract |
| Cheung Tung Shing KS et al. 2018 | Study models reported: in vitro; animal (mouse) · from the abstractCorrection published: Sci Rep. 2019 May 21;9(1):7851. doi: 10.1038/s41598-019-43988-9. |
| Sarker M et al. 2018 | Chemical, structural or analytical study; no biological model reported |
| Kim KH et al. 2018 | Study models reported: in vitro · from the full text |
| Spengler J et al. 2018 | Chemical, structural or analytical study; no biological model reported |
| O'Harte FPM et al. 2018 | Study models reported: in vitro; animal (mouse) · from the abstract |
| Zhang H et al. 2018 | Study models reported: in vitro · from the abstract |
| Nairz M et al. 2017 | Study models reported: in vitro; animal (mouse) · from the abstract |
| Herzig S et al. 2017 | Review article |
| Djillani A et al. 2017 | Study models reported: in vitro; animal (mouse) · from the abstract |
| Okada AK et al. 2017 | Study models reported: in vitro · from the abstract |
| Takahashi D et al. 2017 | Chemical, structural or analytical study; no biological model reported |
| Zhang Y et al. 2017 | Study models reported: in vitro · from the abstract |
| Zhang H et al. 2017 | Study models reported: in vitro · from the abstract |
| Young LM et al. 2017 | Study models reported: in vitro · from the abstract |
| Zhang Y et al. 2017 | Review article |
| Pang X et al. 2016 | Chemical, structural or analytical study; no biological model reported |
| da Silva DC et al. 2016 | Study models reported: in vitro · from the abstract |
| Cobb LJ et al. 2016 | Study models reported: in vitro; animal (rat, mouse) · from the full text |
| Kumar N et al. 2016 | Study models reported: in vitro; animal (rat) · from the abstract |
| Volkova A et al. 2016 | Study models reported: animal (rat) · from the abstract |
| Nederpelt I et al. 2015 | Study models reported: in vitro · from the abstract |
| Malik S et al. 2015 | Study models reported: in vitro · from the abstract |
| Lau J et al. 2015 | Study models reported: in vitro; animal (mini-pig) · from the abstract |
| Lubecka EA et al. 2015 | Study models reported: in vitro · from the abstract |
| Lee C et al. 2015 | Study models reported: in vitro; animal (mouse) · from the full text |
| González-Sales M et al. 2015 | Study models reported: human participants (interventional) · from the abstract |
| Ramos-Álvarez I et al. 2015 | Study models reported: in vitro · from the abstract |
| Cox HD et al. 2014 | Study models reported: in vitro · from the abstract |
| Secher A et al. 2014 | Study models reported: in vitro; animal (rat, mouse) · from the abstract |
| Kazim SF et al. 2014 | Study models reported: animal (mouse) · from the abstract |
| Bataille D et al. 2014 | Review article |
| Choi YL et al. 2014 | Study models reported: in vitro · from the abstract |
| Postma TM et al. 2014 | Chemical, structural or analytical study; no biological model reported |
| Kim DK et al. 2014 | Study models reported: in vitro · from the abstract |
| Kuliawat R et al. 2013 | Study models reported: in vitro; animal (rat) · from the abstract |
| Castelletto V et al. 2013 | Chemical, structural or analytical study; no biological model reported |
| Chin YP et al. 2013 | Study models reported: animal (mouse, rat) · from the abstract |
| Zuo Y et al. 2013 | Study models reported: animal (mouse) · from the abstract |
| Campbell JE et al. 2013 | Review article |
| Ho EN et al. 2012 | Study models reported: in vitro; animal (horse) · from the abstract |
| Esposito S et al. 2012 | Chemical, structural or analytical study; no biological model reported |
| Morgan K et al. 2012 | Study models reported: in vitro · from the abstract |
| Kosinski JR et al. 2012 | Study models reported: in vitro; animal (mouse) · from the full text |
| Yao X et al. 2012 | Study models reported: in vitro · from the abstract |
| Elizondo-Riojas MA et al. 2011 | Chemical, structural or analytical study; no biological model reported |
| Swartjes M et al. 2011 | Study models reported: animal (rat, mouse) · from the abstract |
| Abu Samah NH et al. 2011 | Review article |
| Delhanty PJ et al. 2011 | Review article |
| Thomas A et al. 2011 | Study models reported: in vitro · from the abstract |
| Grunfeld C et al. 2011 | News item |
| Hinkle PM et al. 2011 | Study models reported: in vitro · from the abstract |
| Venneti KC et al. 2010 | Chemical, structural or analytical study; no biological model reported |
| Duan X et al. 2010 | Chemical, structural or analytical study; no biological model reported |
| Chang CH et al. 2010 | Study models reported: in vitro · from the abstract |
| Li B et al. 2010 | Study models reported: animal (mouse) · from the abstract |
| Mazella J et al. 2010 | Study models reported: in vitro; animal (mouse) · from the abstract |
| Hannappel E 2010 | Review article |
| Laimou DK et al. 2010 | Study models reported: in vitro · from the abstract |
| Bryant AP et al. 2010 | Study models reported: in vitro · from the abstract |
| Underwood CR et al. 2010 | Review article |
| Ko YJ et al. 2009 | Chemical, structural or analytical study; no biological model reported |
| Sachon E et al. 2009 | Chemical, structural or analytical study; no biological model reported |
| Bodzioch M et al. 2009 | Study models reported: in vitro · from the abstract |
| Hashimoto Y et al. 2009 | Study models reported: in vitro · from the abstract |
| Chirita RI et al. 2009 | Chemical, structural or analytical study; no biological model reported |
| Yang Y et al. 2009 | Study models reported: in vitro · from the abstract |
| Wang Y et al. 2009 | Review article |
| Champagne K et al. 2008 | Study models reported: in vitro · from the abstract |
| Brines M et al. 2008 | Study models reported: in vitro; animal (rat, mouse, rabbit) · from the full text |
| Nonoyama A et al. 2008 | Chemical, structural or analytical study; no biological model reported |
| Pickart L 2008 | Review article |
| Lula I et al. 2007 | Chemical, structural or analytical study; no biological model reported |
| Sun HQ et al. 2007 | Review article |
| Hannappel E 2007 | Review article |
| Mirabeau O et al. 2007 | Study models reported: in vitro · from the abstract |
| Tomlinson B 2006 | Review article |
| Dolotov OV et al. 2006 | Study models reported: animal (rat) · from the abstract |
| Alba M et al. 2006 | Study models reported: animal (mouse) · from the abstract |
| Tena-Sempere M 2006 | Review article |
| Teichman SL et al. 2005 | Study models reported: human participants (interventional) · from the abstract |
| Han SK et al. 2005 | Study models reported: in vitro; animal (mouse) · from the full text |
| Pogozheva ID et al. 2005 | Study models reported: in vitro · from the abstract |
| Jetté L et al. 2005 | Study models reported: in vitro; animal (rat) · from the abstract |
| Harada M et al. 2004 | Study models reported: in vitro · from the abstract |
| Brines M et al. 2004 | Study models reported: in vitro; animal (mouse) · from the abstract |
| Xiao T et al. 2004 | Study models reported: in vitro · from the abstract |
| Demers A et al. 2004 | Study models reported: in vitro · from the abstract |
| Cavasin MA et al. 2004 | Study models reported: in vitro; animal (rat) · from the abstract |
| Yan M et al. 2004 | Study models reported: in vitro · from the abstract |
| Hudson FM et al. 2004 | Chemical, structural or analytical study; no biological model reported |
| Esposito P et al. 2003 | Review article |
| Khavinson VKh et al. 2003 | Study models reported: in vitro · from the abstract |
| Getting SJ et al. 2003 | Study models reported: in vitro; animal (mouse) · from the abstract |
| Guo B et al. 2003 | Study models reported: in vitro · from the abstract |
| Guerlavais V et al. 2003 | Study models reported: in vitro; animal (rat, beagle dog) · from the abstract |
| Tzakos AG et al. 2003 | Chemical, structural or analytical study; no biological model reported |
| Bodart V et al. 2002 | Study models reported: in vitro · from the abstract |
| Hövelmann S et al. 2002 | Study models reported: in vitro · from the abstract |
| Khavinson VKh 2002 | Review article |
| Silva Elipe MV et al. 2001 | Chemical, structural or analytical study; no biological model reported |
| Hantgan RR et al. 2001 | Study models reported: in vitro · from the abstract |
| Hansen TK et al. 2001 | Study models reported: in vitro; animal (pig) · from the abstract |
| Kotani M et al. 2001 | Study models reported: in vitro; animal (rat) · from the abstract |
| Muir AI et al. 2001 | Study models reported: in vitro · from the abstract |
| Ohtaki T et al. 2001 | Study models reported: in vitro; in vivo (subject not stated) · from the abstract |
| Hashimoto Y et al. 2001 | Study models reported: in vitro · from the abstractCorrection published: Proc Natl Acad Sci U S A 2001 Oct 23;98(22):12854 |
| Smith RG et al. 2001 | Review article |
| Pollard TD et al. 2001 | No abstract available; study type not determined |
| Sanz-Nebot V et al. 2001 | Chemical, structural or analytical study; no biological model reported |
| Jin L et al. 2000 | Chemical, structural or analytical study; no biological model reported |
| Sanz-Nebot V et al. 2000 | Chemical, structural or analytical study; no biological model reported |
| Sanz-Nebot V et al. 2000 | Chemical, structural or analytical study; no biological model reported |
| Hartmann B et al. 2000 | Study models reported: in vitro · from the abstract |
| Whitmore TE et al. 2000 | Chemical, structural or analytical study; no biological model reported |
| Ichiyama T et al. 2000 | Review article |
| Kojima M et al. 1999 | Study models reported: in vitro; in vivo (subject not stated) · from the abstract |
| Miura S et al. 1999 | Study models reported: in vitro · from the abstract |
| Moriarty DF et al. 1999 | Study models reported: in vitro · from the abstract |
| Frolik CA et al. 1999 | Study models reported: in vitro; animal (rat) · from the abstract |
| Bednarek MA et al. 1999 | Study models reported: in vitro · from the abstract |
| Raun K et al. 1998 | Study models reported: in vitro; animal (rat, swine) · from the abstract |
| Walse B et al. 1998 | Chemical, structural or analytical study; no biological model reported |
| Brubaker PL et al. 1997 | Study models reported: in vitro; animal (rat) · from the abstract |
| Yang Yk et al. 1997 | Study models reported: in vitro · from the abstract |
| Arvat E et al. 1997 | Study models reported: human participants (interventional) · from the abstract |
| Deacon CF et al. 1995 | Study models reported: in vitro · from the abstract |
| Hruby VJ et al. 1995 | Study models reported: in vitro · from the abstract |
| Wu H et al. 1994 | Study models reported: in vitro · from the abstract |
| Lapthorn AJ et al. 1994 | Chemical, structural or analytical study; no biological model reported |
| Lane TF et al. 1994 | Study models reported: in vitro; in vivo (subject not stated) · from the abstract |
| Müller A et al. 1994 | Chemical, structural or analytical study; no biological model reported |
| Kato T et al. 1993 | Chemical, structural or analytical study; no biological model reported |
| Chen R et al. 1993 | Study models reported: in vitro · from the abstract |
| Mentlein R et al. 1993 | Study models reported: in vitro · from the abstract |
| Katayama K et al. 1993 | Study models reported: in vitro · from the abstract |
| Orskov C et al. 1993 | Study type not determinable from the abstract |
| Mayo KE 1992 | Study models reported: in vitro · from the abstract |
| Eng J et al. 1992 | Study models reported: in vitro · from the abstract |
| Eng J 1992 | Study type not determinable from the abstract |
| Hiltz ME et al. 1991 | Study models reported: animal (mouse) · from the abstract |
| Hock FJ et al. 1991 | Study models reported: in vitro · from the abstract |
| Meyer JP et al. 1991 | Chemical, structural or analytical study; no biological model reported |
| Hino J et al. 1990 | Chemical, structural or analytical study; no biological model reported |
| Kambayashi Y et al. 1990 | Chemical, structural or analytical study; no biological model reported |
| Miller DM et al. 1990 | Study models reported: in vitro · from the abstract |
| Al-Obeidi F et al. 1989 | Study models reported: in vitro · from the abstract |
| Miyata A et al. 1989 | Study models reported: in vitro · from the abstract |
| Orskov C et al. 1989 | Study models reported: in vitro · from the abstract |
| Sakina K et al. 1988 | Chemical, structural or analytical study; no biological model reported |
| Blache P et al. 1988 | Study models reported: in vitro · from the abstract |
| Kreymann B et al. 1987 | Study models reported: in vitro; human participants (interventional) · from the abstract |
| Cooper GJ et al. 1987 | Study models reported: in vitro · from the abstract |
| Westermark P et al. 1987 | Study models reported: in vitro · from the abstract |
| Mojsov S et al. 1987 | Study models reported: in vitro · from the abstract |
| Griffin JF et al. 1986 | Chemical, structural or analytical study; no biological model reported |
| Heiman ML et al. 1985 | Study models reported: in vitro · from the abstract |
| Fujii N et al. 1984 | Chemical, structural or analytical study; no biological model reported |
| Moody AJ et al. 1984 | Study models reported: in vitro · from the abstract |
| Graf MV et al. 1984 | Review article |
| Spiess J et al. 1983 | Chemical, structural or analytical study; no biological model reported |
| Laussac JP et al. 1983 | Chemical, structural or analytical study; no biological model reported |
| Freedman JH et al. 1982 | Chemical, structural or analytical study; no biological model reported |
| Lau SJ et al. 1981 | Study models reported: in vitro · from the abstract |
| Sawyer TK et al. 1980 | Study models reported: in vitro · from the full text |
| Fiddes JC et al. 1980 | Study models reported: in vitro · from the abstract |
| Fiddes JC et al. 1979 | Study models reported: in vitro · from the abstract |
| Dutta AS et al. 1978 | Study models reported: animal (rat) · from the abstract |
| Schoenenberger GA et al. 1978 | Study models reported: animal (rabbit) · from the abstract |
| Schlesinger DH et al. 1977 | No abstract available; study type not determined |
| Bleich HE et al. 1976 | Chemical, structural or analytical study; no biological model reported |
| Simantov R et al. 1976 | Study models reported: in vitro · from the abstract |
| Hughes J et al. 1975 | Chemical, structural or analytical study; no biological model reported |
| Morgan FJ et al. 1975 | Study models reported: in vitro · from the abstract |
| Niall HD et al. 1974 | Chemical, structural or analytical study; no biological model reported |
| Carlsen RB et al. 1973 | No abstract available; study type not determined |
| Brewer HB Jr et al. 1972 | Chemical, structural or analytical study; no biological model reported |
| Baba Y et al. 1971 | No abstract available; study type not determined |
| Burgus R et al. 1970 | Chemical, structural or analytical study; no biological model reportedCorrection published: Nature. 1970 May 2;226(5244):479 |
| Boler J et al. 1969 | Chemical, structural or analytical study; no biological model reported |
| Niall HD et al. 1969 | Chemical, structural or analytical study; no biological model reported |
| Suzuki K et al. 1966 | Chemical, structural or analytical study; no biological model reported |
| Barger G et al. 1918 | Chemical, structural or analytical study; no biological model reported |