Lot certificates published
Plain, secure packaging

Research entities

Compound Directory

An alphabetical directory of published research compounds, scientific aliases, development codes, and verified identifiers.

102 records

Filters read the fields stored in each record. A record with no assigned class, listed target, listed sequence, recorded terminal group or recorded ring closure is grouped under its own option; it may still have one that this Library has not yet verified. A small molecule, peptidomimetic or glycoprotein that declares no terminal group is listed as not a single peptide chain. Residue counts cover records with a listed sequence only. Filtered views can be shared by copying the page address.

Mitochondrial-derived peptides

HNGF6A

HNGF6A · F6A/S14G-humanin

HNGF6A is a synthetic humanin analog with F6A and S14G substitutions, described as non-IGFBP-3-binding in a comparative disposition study.

CAS 1093111-54-6PubChem CID 90489015

Mitochondrial-derived peptides

HNG ([Gly14]-Humanin)

HNG · S14G-humanin · S14G-HN · Humanin-G

HNG is a synthetic single-substitution analog of humanin carrying glycine in place of serine at position 14.

CAS 330936-70-4PubChem CID 16135997

Linear melanocortin analogs

Melanotan I (Afamelanotide)

Melanotan I · Melanotan-1 · MT-I · MT-1 · NDP-MSH · NDP-alpha-MSH · CUV1647 · MBJ05

Afamelanotide, widely supplied as Melanotan I, is a linear thirteen-residue analog of alpha-melanocyte-stimulating hormone carrying norleucine and D-phenylalanine substitutions.

CAS 75921-69-6PubChem CID 16197727

Melanocortin receptor ligands

alpha-MSH

α-MSH · alpha-MSH · alpha-melanotropin · Melanotropin alpha

alpha-MSH is the endogenous thirteen-residue melanocortin peptide hormone from which several of the synthetic compounds in this library are derived.

CAS 581-05-5PubChem CID 16133793

Amylin and calcitonin receptor agonists

Amylin (human IAPP)

Human islet amyloid polypeptide · IAPP · hIAPP · Amlintide

Amylin is the endogenous 37-residue human pancreatic peptide hormone, co-secreted with insulin, from which pramlintide and cagrilintide are both derived.

CAS 122384-88-7PubChem CID 16132430

Growth hormone secretagogues

Anamorelin

ONO-7643 · RC-1291 · ST-1291

Anamorelin is a nonpeptide small-molecule agonist at the ghrelin receptor, structurally unrelated to the peptide secretagogues that share its target.

CAS 249921-19-5PubChem CID 9828911

Angiotensin II (Ile5, free peptide)

AII · AngII

Angiotensin II is a linear octapeptide composed of eight L-amino-acid residues. This record describes the Ile5 free peptide with unmodified amino and carboxyl termini.

PubChem CID 172198

Regulatory peptide fragment analogs

AOD-9604

Tyr-hGH(177-191) · AOD9604

AOD-9604 is a synthetic, sixteen-residue human GH1 fragment analog specified with an N-terminal tyrosine, free termini and one intramolecular disulfide. AOD-9604 is used here as a provisional development-code name; an INN or USAN has not been established for this record.

CAS 221231-10-3PubChem CID 71300630

Apelin-13 (unmodified)

Apelin-13 is a 13-residue peptide with an N-terminal glutamine and a C-terminal phenylalanine. This record describes the unmodified parent with free terminal groups.

PubChem CID 25078060

Arginine vasopressin

Arginine-vasopressin · AVP

Arginine vasopressin is a nine-residue peptide with a free N-terminus, a C-terminal glycinamide and a Cys1-Cys6 disulfide.

CAS 113-79-1PubChem CID 644077

Regenerative peptides

BPC-157

Bepecin · BPC 15

BPC-157 is a synthetic fifteen-residue peptide corresponding to a partial sequence of body protection compound, a protein reported to have been isolated from human gastric juice.

CAS 137525-51-0PubChem CID 9941957

Bradykinin

Bradykinin is a linear nonapeptide composed of standard amino-acid residues, with free N and C termini.

CAS 58-82-2PubChem CID 439201

Cyclic melanocortin analogs

PT-141 (Bremelanotide)

Bremelanotide · PT 141 · PT-141 free base · PT-141

PT-141, canonically bremelanotide, is a synthetic cyclic heptapeptide melanocortin receptor agonist, structurally the C-terminal free acid of the Melanotan II lactam scaffold.

CAS 189691-06-3PubChem CID 9941379

Amylin and calcitonin receptor agonists

Cagrilintide

AM833 · AM-833 · NNC0174-0833

Cagrilintide is a long-acting synthetic amylin analog, lipidated and disulfide-cyclized, characterised at the calcitonin receptor and at amylin receptor complexes.

CAS 1415456-99-3PubChem CID 171397054

L-Carnosine

β-Alanyl-L-histidine

Carnosine is the dipeptide β-alanyl-L-histidine. This record describes the free parent, with an uncapped amino end and a free carboxyl end.

CAS 305-84-0PubChem CID 439224

GnRH peptide analogs

Cetrorelix

cetrorelixum

Cetrorelix is a synthetic linear decapeptide with defined D/L configuration and nonstandard residues, an acetylated N terminus and an amidated C terminus. This record describes the parent without counterion.

CAS 120287-85-6PubChem CID 25074887

ARA-290

ARA 290 · Cibinetida · Cibinetidum · PHBSP

Cibinetide is a synthetic peptide corresponding to a surface region of erythropoietin, characterized in the literature as a selective agonist at a heteromeric receptor complex distinct from the erythropoietin receptor homodimer.

CAS 1208243-50-8PubChem CID 91810664

GHRH analogs

CJC-1295

CJC 1295

CJC-1295 designates a tetrasubstituted analog of human growth hormone-releasing factor residues 1 to 29, reported to act at the GRF receptor on the anterior pituitary.

PubChem CID 56841945

Neuropeptides and derived fragments

Human corticotropin-releasing factor (1–41) amide

hCRF · Human corticotropin-releasing factor · Rat corticotropin-releasing factor

Corticorelin (human/rat sequence) is a 41-residue peptide with a free N terminus and an amidated C-terminal isoleucine.

CAS 86784-80-7

Melanocortin receptor ligands

Cosyntropin (ACTH 1-24)

Tetracosactide · ACTH(1-24) · alpha 1-24 corticotropin

Cosyntropin is the synthetic 1-24 fragment of adrenocorticotropic hormone, the melanocortin ligand of the MC2R branch.

CAS 16960-16-0PubChem CID 16133751

GnRH peptide analogs

Degarelix

Degarelixum

Degarelix is a synthetic linear decapeptide with an acetylated N terminus, an amidated C terminus and explicitly configured nonstandard residues. This record describes the parent without acetate or hydrate components.

CAS 214766-78-6PubChem CID 16136245

Neuropeptides and derived fragments

DSIP

DSIP · Delta-sleep-inducing peptide

DSIP is a synthetic nonapeptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, first isolated and sequenced in 1978.

CAS 62568-57-4PubChem CID 68816

Dermorphin

Dermorphin is a seven-residue peptide with D-alanine at position 2, an uncapped N-terminus and a C-terminal amide. This record describes the neutral parent separately from modified derivatives and counterion-containing preparations.

CAS 77614-16-5PubChem CID 5485199

Desmopressin

dDAVP · 1-deamino-8-D-arginine vasopressin · 1-desamino-8-D-arginine vasopressin

Desmopressin is a synthetic cyclic peptide construction containing eight amino-acid units and an N-terminal 3-mercaptopropanoyl unit. Its conventional numbering spans nine positions. This record describes the anhydrous parent without acetate or water of crystallization.

CAS 16679-58-6PubChem CID 5311065

Aromatic cationic tetrapeptides

Elamipretide

Bendavia · SS-31

Elamipretide is a synthetic linear tetrapeptide with D-arginine, L-2′,6′-dimethyltyrosine, L-lysine and L-phenylalanine in that order, a free N-terminal amino group and a C-terminal primary carboxamide.

CAS 736992-21-5PubChem CID 11764719

Enfuvirtide

T20 · T-20 · DP-178

Enfuvirtide is a synthetic linear peptide comprising 36 L-amino-acid residues, with an acetylated N terminus and a C-terminal amide.

CAS 159519-65-0PubChem CID 16130199

Epitalon

Epithalon · Epithalone · AEDG peptide

Epitalon is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, described in the source literature as a short peptide designed following work on pineal tissue extracts.

CAS 307297-39-8PubChem CID 219042

Eptifibatide

Eptifibatidum · Eptifibatida

Eptifibatide is a synthetic peptide containing L-homoarginine and a disulfide closure connecting an N-terminal 3-mercaptopropanoyl unit to the C-terminal cysteinamide.

PubChem CID 448812

Growth hormone secretagogues

Examorelin (Hexarelin)

Hexarelin · EP-23905 · MF-6003

Examorelin, widely supplied as hexarelin, is a synthetic hexapeptide growth hormone secretagogue carrying a 2-methylated D-tryptophan.

CAS 140703-51-1PubChem CID 6918297

GLP-1 receptor peptide analogs

Exenatide

Exendin-4

Exenatide is synthetic exendin-4, a 39-residue peptide with an N-terminal histidine and a C-terminal serine amide; the natural peptide was isolated from Heloderma suspectum venom and characterized as a member of the glucagon superfamily. Horváth et al. (PMID 37528104) place the exendins among the gastrointestinal peptides of the glucagon family.

CAS 141758-74-9PubChem CID 45588096

Neuropeptides and derived fragments

Galanin (human 1-30)

GAL · Galanin(1-30)

Galanin is a thirty-residue human neuropeptide acting through the galanin receptor family, and the reference ligand against which spexin's receptor selectivity is measured.

CAS 119418-04-1PubChem CID 16133823

Growth hormone secretagogues

Human Octanoyl-Ghrelin

Lenomorelin · Human acyl-ghrelin · Acyl-ghrelin

Human octanoyl-ghrelin is the endogenous 28-residue acylated peptide ligand of the ghrelin receptor, carrying an n-octanoyl ester on serine 3.

CAS 258279-04-8PubChem CID 91668172

Growth hormone secretagogues

GHRP-6

Hexapeptide-2 · Growth hormone-releasing peptide-6

GHRP-6 is a synthetic hexapeptide with a C-terminal amide, characterized as an agonist at the growth hormone secretagogue receptor.

CAS 87616-84-0PubChem CID 9919153

Incretin and glucagon receptor ligands

Glucagon

Glucagon(1-29)

Glucagon is the endogenous 29-residue pancreatic hormone and the native ligand of the glucagon receptor. Horváth et al. (PMID 37528104) place glucagon among the gastrointestinal peptides of the glucagon family.

CAS 16941-32-5PubChem CID 16132283

Incretin and glucagon receptor ligands

GLP-1(7-36) amide

GLP-1(7-36)amide · GLP-1 7-36 amide

GLP-1(7-36) amide is an endogenous processing form of glucagon-like peptide-1 and the native ligand against which the GLP-1 receptor agonists in this library are compared. Deacon et al. (PMID 7556682) isolated this form from human colon and conclude that it is a product of proglucagon processing. Horváth et al. (PMID 37528104) place GLP-1 among the gastrointestinal peptides of the glucagon family.

CAS 107444-51-9PubChem CID 16133831

Incretin and glucagon receptor ligands

GLP-1(7-37)

GLP-1 7-37 · GLP-I(7-37) · Insulinotropin

GLP-1(7-37) is an endogenous processing form of glucagon-like peptide-1 retaining a C-terminal glycine, and the structural reference for several acylated GLP-1 analogs. Mojsov et al. (PMID 3543057) describe the glucagon-like peptides as liberated from proglucagon in both the pancreas and the intestine. Horváth et al. (PMID 37528104) place GLP-1 among the gastrointestinal peptides of the glucagon family.

CAS 106612-94-6PubChem CID 16133830

Incretin and glucagon receptor ligands

GIP(1-42)

GIP · Gastric inhibitory polypeptide · Glucose-dependent insulinotropic peptide

GIP is a 42-residue endogenous incretin hormone and the native ligand of the GIP receptor. Horváth et al. (PMID 37528104) place GIP among the gastrointestinal peptides of the glucagon family.

CAS 100040-31-1PubChem CID 131954558

Glutathione (reduced)

Reduced glutathione · GSH · γ-L-Glutamyl-L-cysteinylglycine

Reduced glutathione is γ-L-glutamyl-L-cysteinylglycine, an acyclic three-unit peptide with a free cysteine thiol. The first amide bond uses the glutamyl γ-carboxyl group.

CAS 70-18-8PubChem CID 124886

Neuropeptides and derived fragments

Gonadorelin (GnRH-I)

GnRH-I · Gonadotropin-releasing hormone · LHRH · LH-RH

Gonadorelin is the ten-residue hypothalamic releasing hormone GnRH-I, carrying an N-terminal pyroglutamate and a C-terminal amide.

CAS 33515-09-2PubChem CID 638793

Thymosin-related peptides

Ac-SDKP (Goralatide)

Ac-SDKP · Seraspenide · N-acetyl-seryl-aspartyl-lysyl-proline

Ac-SDKP is the acetylated N-terminal tetrapeptide of thymosin beta-4, generated from the parent by sequential enzymatic processing.

CAS 120081-14-3PubChem CID 65938

Goserelin

Goserelin is a synthetic peptide parent containing an L-pyroglutamyl first unit, an O-tert-butyl-D-seryl unit at position 6 and a carbamoylhydrazide terminus. This record excludes counterions and water components.

PubChem CID 5311128

hCG (Human chorionic gonadotropin)

hCG

Human chorionic gonadotropin (hCG) is a glycoprotein hormone made of two different subunits, alpha and beta, that associate without a covalent bond between the chains. This record describes the intact two-chain hormone. It is not a record of either subunit alone or of any fragment.

Human GLP-2(1-33)

GLP-2 · Glucagon-like peptide-2 · Human GLP-2 · hGLP-2

Human GLP-2(1-33) is a linear 33-residue peptide with a free amino terminus and a C-terminal carboxyl group. This record describes the unmodified parent covalent structure. Orskov et al. (PMID 2714431) characterize human and pig intestinal GLP-2 as a proglucagon processing product. Horváth et al. (PMID 37528104) place GLP-2 among the gastrointestinal peptides of the glucagon family.

CAS 223460-79-5PubChem CID 71300624

Mitochondrial-derived peptides

Humanin (HN)

HN

Humanin is a 24-residue peptide encoded within the mitochondrial 16S ribosomal RNA gene, and the first-described member of the mitochondrial-derived peptide family.

CAS 330936-69-1PubChem CID 16131438

Icatibant

Icatibantum · HOE 140

Icatibant is a synthetic linear decapeptide containing D-configured and nonproteinogenic amino-acid units. This record describes its counterion-free parent peptide.

CAS 130308-48-4PubChem CID 6918173

Growth hormone secretagogues

Ipamorelin

NNC 26-0161

Ipamorelin is a synthetic pentapeptide with a C-terminal amide, characterized in its original report as a growth hormone secretagogue acting through a GHRP-like receptor rather than the GHRH receptor.

CAS 170851-70-4PubChem CID 9831659

Kisspeptins

Kisspeptin-10

KP-10 · Metastin (45-54) · Human metastin 45-54

Kisspeptin-10 is the amidated ten-residue C-terminal fragment represented by the human KISS1-derived kisspeptin sequence. Foundational records identify KISS1 peptides as ligands of GPR54, now KISS1R.

CAS 374675-21-5PubChem CID 25240297

Kisspeptins

Kisspeptin-14

KP-14 · Metastin(41-54)

Kisspeptin-14 is a KISS1-derived peptide isolated from human placental extracts, containing kisspeptin-10 as its C-terminal decapeptide, and an agonist at the kisspeptin receptor.

CAS 374675-19-1PubChem CID 171916517

Melanocortin fragment peptides

KPV

Lys-Pro-Val · alpha-MSH (11-13) · MSH (11-13)

KPV is a synthetic tripeptide, Lys-Pro-Val, corresponding to the C-terminal three residues of alpha-melanocyte-stimulating hormone.

CAS 67727-97-3PubChem CID 125672

Matrikine-derived peptides

KTTKS (Pentapeptide-4)

Pentapeptide-4 · Collagen pentapeptide

KTTKS is the unmodified pentapeptide from type I procollagen that forms the peptide backbone of the palmitoylated cosmetic ingredient Matrixyl.

CAS 149128-48-3PubChem CID 9959565

Larazotide

larazotidum · larazotida

Larazotide is a linear octapeptide with free N and C termini. This record describes the defined parent peptide composition separately from counterion-containing and hydrated preparations.

CAS 258818-34-7PubChem CID 9810532

GnRH peptide analogs

Leuprolide (leuprorelin)

Leuprolide · Leuprorelinum

Leuprorelin, also called leuprolide, is a synthetic nine-residue peptide with an L-pyroglutamyl residue at position 1, D-leucine at position 6 and an N-ethylamide on the C-terminal proline. This record describes the parent peptide without counterion or hydrate.

CAS 53714-56-0PubChem CID 657181

Linaclotide

Linaclotidum · Linaclotida

Linaclotide is a synthetic 14-residue peptide with free termini and three intramolecular disulfide bridges.

CAS 851199-59-2PubChem CID 16158208

GLP-1 receptor peptide analogs

Liraglutide

NN2211

Liraglutide is an acylated peptide analog of glucagon-like peptide-1, characterized against the GLP-1 receptor.

CAS 204656-20-2PubChem CID 16134956

Growth hormone secretagogues

Macimorelin

AEZS-130 · JMV 1843 · EP-1572

Macimorelin is a gem-diamino peptidomimetic agonist at the ghrelin receptor.

CAS 381231-18-1PubChem CID 9804938

Multi-receptor incretin analogs

Mazdutide

IBI362 · IBI-362 · LY3305677 · LY-3305677 · IBI362 · LY3305677

Mazdutide is a lipidated synthetic peptide classified as a GLP-1 and glucagon receptor dual agonist, built on an oxyntomodulin-derived backbone.

CAS 2259884-03-0PubChem CID 172871914

Cyclic melanocortin analogs

Melanotan II

Melanotan-II · MT-II · MT-2

Melanotan II is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone, closed by a lactam bridge between an aspartate and a lysine side chain.

CAS 121062-08-6PubChem CID 92432

Neuropeptides and derived fragments

Met-enkephalin

Methionine enkephalin · Methionine-enkephalin · [Met5]enkephalin

Met-enkephalin is a linear five-residue peptide with the sequence Tyr-Gly-Gly-Phe-Met and free amino and carboxyl termini.

CAS 58569-55-4PubChem CID 443363

Mitochondrial-derived peptides

MOTS-c

Mitochondrial open reading frame of the 12S rRNA-c

MOTS-c is a sixteen-amino-acid peptide encoded by a short open reading frame within the mitochondrial 12S rRNA, rather than by the nuclear genome.

CAS 1627580-64-6PubChem CID 146675088

Regulatory peptide fragment analogs

N-Acetyl Selank Amidate

N-Acetyl Selank Amidate is the Selank heptapeptide with an acetyl group on the N-terminal threonine residue and an amide at the C-terminal proline. These covalent terminal changes define a distinct molecule.

Regulatory peptide fragment analogs

N-Acetyl Semax Amidate

N-Acetyl Semax Amidate is the Semax heptapeptide with an acetyl group on the N-terminal methionine residue and an amide at the C-terminal proline. These covalent terminal changes define a distinct molecule.

PubChem CID 172638603

Human brain natriuretic peptide (1–32)

Human brain natriuretic peptide (1–32) is a 32-residue peptide with free termini and one intramolecular disulfide between Cys10 and Cys26.

CAS 124584-08-3

Noopept (Omberacetam)

N-phenylacetyl-L-prolylglycine ethyl ester · omberacetamum · ombéracétam · GVS-111

Omberacetam is N-phenylacetyl-L-prolylglycine ethyl ester, a terminally modified dipeptide. This record describes the neutral parent.

CAS 157115-85-0PubChem CID 180496

Nonpeptide receptor agonists

Orforglipron

LY3502970

Orforglipron is a synthetic nonpeptide molecule characterized as a selective, high-affinity agonist at the human GLP-1 receptor.

CAS 2212020-52-3PubChem CID 137319706

Incretin and glucagon receptor ligands

Oxyntomodulin

OXM · Glucagon-37

Oxyntomodulin is an endogenous proglucagon-derived peptide containing the complete glucagon sequence plus an eight-residue C-terminal extension, with reported activity at both the GLP-1 and glucagon receptors. A review by Bataille and Dalle (PMID 25115338) describes oxyntomodulin as a member of the glucagon family; that is a review-level family attribution.

PubChem CID 121494088

Neuropeptides and derived fragments

Oxytocin

Oxytocin is a mature nine-residue peptide with an intramolecular disulfide and a terminal carboxamide. This identity record is scoped to the Leu8 form.

Neurotrophic peptide mimetics

P021 (P21)

P21 · P-21 · Peptide 021

P021 is a small acetylated tetrapeptide carrying an adamantane-derived C-terminal extension, designed as a CNTF-derived peptide mimetic.

CAS 1246751-68-7PubChem CID 56599151

Neuropeptides and derived fragments

PACAP-38

PACAP 38

PACAP-38 is a linear 38-residue peptide with a free N-terminal histidine and a C-terminal lysinamide.

CAS 124123-15-5

Matrikine-derived peptides

Matrixyl

Pal-KTTKS · Palmitoyl-KTTKS · Palmitoyl pentapeptide-3

Palmitoyl pentapeptide-4 is the pentapeptide KTTKS with an N-terminal palmitoyl group, corresponding to a fragment sequence of type I procollagen.

CAS 214047-00-4PubChem CID 9897237

Matrikine-derived peptides

Pal-GHK (Palmitoyl Tripeptide-1)

Pal-GHK · N-palmitoyl-GHK · C16-GHK · Palmitoyl oligopeptide

Pal-GHK is the N-palmitoylated derivative of the GHK tripeptide, used as a cosmetic ingredient and as an analytical internal standard.

CAS 147732-56-7PubChem CID 10231864

Regulatory peptide fragment analogs

PE 22-28

PE(22-28) · Sortilin propeptide (22-28)

PE 22-28 is a synthetic heptapeptide corresponding to residues 22 to 28 of the sortilin propeptide. It is not a fragment of spexin; see the nomenclature note.

PubChem CID 165437303

Plecanatide

plecanatidum · plécanatide · plecanatida

Plecanatide is a synthetic 16-residue peptide with free termini and two intramolecular disulfide bridges.

CAS 467426-54-6PubChem CID 70693500

Growth hormone secretagogues

Pralmorelin (GHRP-2)

GHRP-2 · Growth hormone-releasing peptide-2 · KP-102

Pralmorelin is a synthetic hexapeptide growth hormone secretagogue acting at the ghrelin receptor, containing three D-configured residues and a naphthylalanine substitution.

CAS 158861-67-7PubChem CID 6918245

Amylin and calcitonin receptor agonists

Pramlintide

AC137

Pramlintide is an engineered analog of human amylin carrying three proline substitutions, designed to address the aggregation behaviour of the native human sequence.

CAS 151126-32-8PubChem CID 70691388

Copper-binding peptides · Matrikine-derived peptides

GHK (Prezatide)

GHK · Glycyl-L-histidyl-L-lysine · Tripeptide-1 · NSC-379527

GHK is the uncomplexed tripeptide ligand of the GHK-copper complex, identified in 1977 as a growth-modulating tripeptide from human plasma.

CAS 49557-75-7PubChem CID 73587

Copper-binding peptides · Matrikine-derived peptides

GHK-Cu

Copper tripeptide-1 · GHK copper · Cu-GHK

Prezatide copper is the Cu(II) coordination complex of the tripeptide glycyl-L-histidyl-L-lysine. The copper ion is part of the declared molecular identity and distinguishes this record from the free tripeptide.

CAS 89030-95-5PubChem CID 10111685

Neuropeptides and derived fragments

TRH (thyrotropin-releasing hormone)

Thyrotropin-releasing hormone · TRH · Thyrotropin-releasing factor · TRF

Protirelin is a tripeptide comprising L-pyroglutamyl, L-histidyl and L-prolinamide units in that order.

CAS 24305-27-9PubChem CID 638678

Multi-receptor incretin analogs

Retatrutide

LY3437943

Retatrutide, development code LY3437943, is a single peptide characterized as an agonist at GCGR, GIPR, and GLP-1R in its discovery record.

CAS 2381089-83-2

Salmon calcitonin

Calcitonin salmon

Salmon calcitonin is a 32-residue peptide with a free N terminus, C-terminal prolinamide and a Cys1-Cys7 disulfide. This record describes the parent without counterion or hydration components.

CAS 47931-85-1

Human secretin

Human secretin is a linear 27-residue peptide with a free N-terminal histidine and a C-terminal valine amide.

CAS 108153-74-8

Regulatory peptide fragment analogs

Selank

Selanc · Tuftsin-Pro-Gly-Pro · TP-7 · TP-7

Selank is a synthetic heptapeptide consisting of the tetrapeptide tuftsin extended at the C-terminus with the tripeptide Pro-Gly-Pro.

CAS 129954-34-3PubChem CID 11765600

GLP-1 receptor peptide analogs

Semaglutide

NN9535 · NNC 0113-0217

Semaglutide is an acylated peptide analog of glucagon-like peptide-1. Its discovery record identifies two amino-acid substitutions and derivatization at Lys26.

CAS 910463-68-2PubChem CID 56843331

Regulatory peptide fragment analogs

Semax

ACTH(4-7)-Pro-Gly-Pro

Semax is a synthetic heptapeptide corresponding to residues 4 to 7 of adrenocorticotropic hormone extended at the C-terminus with the tripeptide Pro-Gly-Pro.

CAS 80714-61-0PubChem CID 9811102

GHRH analogs

Sermorelin

GRF(1-29) · Sermorelina · Sermorelinum

Sermorelin is the synthetic peptide corresponding to residues 1 to 29 of human growth hormone-releasing factor, the unmodified parent fragment from which several longer-acting analogs are derived.

CAS 86168-78-7PubChem CID 16132413

Cyclic melanocortin analogs · Melanocortin receptor ligands

Setmelanotide

RM-493 · BIM-22493 · IRC-022493

Setmelanotide is a synthetic disulfide-cyclized octapeptide characterised as an MC4R-preferring melanocortin receptor agonist. A review by Swan et al. (PMID 38834138) describes setmelanotide as an analogue of alpha-melanocyte-stimulating hormone; that is a review-level parent attribution, not a residue-by-residue design account.

CAS 920014-72-8PubChem CID 11993702

Cyclic melanocortin analogs · Melanocortin receptor ligands

SHU9119

SHU-9119 · SHU 9119

SHU9119 is a cyclic lactam melanocortin analog whose receptor behaviour is subtype-dependent: antagonist at some melanocortin receptors and agonist at others. Gimenez et al. (PMID 35404053) describe SHU9119 as a cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone.

CAS 168482-23-3PubChem CID 9898183

Neuropeptides and derived fragments

CCK-8 (sulfated)

Sulfated cholecystokinin octapeptide · O-sulfated CCK-8

Sincalide is a linear eight-residue peptide with Tyr2 O-sulfation, a free N terminus and a C-terminal phenylalanine amide.

CAS 25126-32-3PubChem CID 9833444

Mitochondrial-derived peptides

SHLP2

SHLP-2

SHLP2 is a 26-residue peptide assigned to a small open reading frame within the mitochondrial 16S rRNA region. Its experimental characterization includes receptor screening, protein-interaction assays and targeted peptide detection.

CAS 1191923-93-9PubChem CID 171716852

Mitochondrial-derived peptides

SHLP3

SHLP-3

SHLP3 is a 38-residue peptide from the same mitochondrial region as humanin, characterised principally through the study that named the series.

Mitochondrial-derived peptides

SHLP6

SHLP-6

SHLP6 is a 20-residue peptide assigned to the mitochondrial 16S rRNA region and distinguished from other SHLP members by its sequence and reported cellular response.

PubChem CID 16208939

Neuropeptides and derived fragments

Spadin

Spadin is a sortilin-propeptide-derived peptide reported to interact with sortilin and to inhibit the TREK-1 potassium channel, and the parent design from which PE 22-28 was derived.

CAS 1270083-24-3PubChem CID 91826106

Neuropeptides and derived fragments

Spexin

SPX · Spexin-1 · NPQ

Spexin is an endogenous fourteen-residue amidated neuropeptide identified by computational screening of the human proteome, and a ligand of galanin receptors 2 and 3.

CAS 1370290-58-6PubChem CID 122705996

Multi-receptor incretin analogs

Survodutide

BI 456906 · BI-456906 · BI 456906

Survodutide is a lipidated synthetic peptide agonist at both the GLP-1 receptor and the glucagon receptor, built on a modified glucagon-family backbone with a branched side-chain linker.

CAS 2805997-46-8PubChem CID 171378821

Angiotensin-(1-7)

Angiotensin (1-7) · Ang-(1-7) · Talfirastidum · Talfirastida · TXA127

Talfirastide, also called Angiotensin-(1-7), is a linear all-L heptapeptide with sequence Asp–Arg–Val–Tyr–Ile–His–Pro, an uncapped amino terminus and a C-terminal carboxyl group.

CAS 51833-78-4PubChem CID 123805

Regulatory peptide fragment analogs

TB-500

N-acetyl-thymosin beta-4 (17-23)

Analytical studies have identified an N-terminally acetylated heptapeptide with the residue sequence LKKTETQ in material labeled TB-500. The designation alone does not establish the complete molecular identity of another preparation.

CAS 885340-08-9PubChem CID 62707662

Teriparatide

Human parathyroid hormone (1-34)

Teriparatide is the linear 34-residue peptide corresponding to residues 1-34 of human parathyroid hormone, with a free amino terminus and a free C-terminal carboxyl group. This record describes the peptide without counterion.

CAS 52232-67-4PubChem CID 16133850

GHRH analogs

Tesamorelin

TH9507

Tesamorelin is a synthetic analog of human growth hormone-releasing factor, characterized in the literature as a GRF analog acting at the GHRH receptor.

CAS 218949-48-5PubChem CID 16137828

Melanocortin receptor ligands

THIQ

THIQ is a nonpeptide small-molecule agonist at the melanocortin-4 receptor, included here as the nonpeptide comparator to the melanocortin peptides.

CAS 312637-48-2PubChem CID 9938402

Thymosin alpha-1

Thymosin alpha1 · Thymosin α1

Thymalfasin, also called thymosin alpha-1, is a linear 28-residue peptide. Its primary structural candidate corresponds to the N-terminal region of prothymosin alpha after the initiator methionine.

Thymosin-related peptides

Thymosin beta-4

Thymosin b4 · Tbeta4 · TB4

Thymosin beta-4 is an N-terminally acetylated peptide originally isolated from a thymic tissue fraction and subsequently characterized as a G-actin-sequestering peptide.

CAS 77591-33-4PubChem CID 16132341

Multi-receptor incretin analogs

Tirzepatide

LY3298176

Tirzepatide is a fatty-acid-modified synthetic peptide characterized in its discovery record as having agonist activity at both the GIP receptor and the GLP-1 receptor.

CAS 2023788-19-2PubChem CID 166567236

GnRH peptide analogs

Triptorelin

Triptorelinum

Triptorelin is a synthetic ten-residue peptide with an L-pyroglutamyl residue at position 1, D-tryptophan at position 6 and a C-terminal glycinamide. This record describes the parent peptide without counterion.

CAS 57773-63-4PubChem CID 25074470

Browse by compound class