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Catalog/CJC-1295 (With DAC)
CJC-1295 (With DAC)
#1059
Lyophilized Peptide

CJC-1295 (With DAC) 2mg

CJC-1295 with Drug Affinity Complex (DAC) is a tetrasubstituted analog of human growth hormone-releasing factor residues 1-29 (D-Ala2, Gln8, Ala15, Leu27) extended by a C-terminal lysine that carries a 3-maleimidopropionamide group, the drug affinity complex. Jetté et al. (2005) identified CJC-1295 among hGRF(1-29)-albumin bioconjugates designed to bind serum albumin. This listing contains 2mg of lyophilized material. Supplied strictly for in-vitro research and laboratory use only. Not for human or animal use.

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Single (2mg)$44.99

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Mechanism of Action

CJC-1295 acts at the GHRH (GRF) receptor on anterior pituitary somatotrophs. Jetté et al. (2005) reported that albumin-conjugated hGRF(1-29) derivatives, including CJC-1295, showed increased stability against dipeptidyl peptidase-IV and stimulated GH secretion in cultured rat anterior pituitary cells, and detected CJC-1295 immunoreactivity at the serum-albumin band in rat plasma beyond 24 h.

Properties

CAS Number

446262-90-4

Molecular Formula

C₁₆₅H₂₆₉N₄₇O₄₆

Molecular Weight

3647.2 Da

Half-Life

Not established by the cited study

Storage

Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 14 days.

Shipping & Delivery

  • Same-day dispatch on orders placed before 2 PM MST (Arizona — no daylight saving).
  • US shipping from $5. Free Priority on orders $100+ (before discounts).
  • Plain, unmarked packaging — no branding or product names on the outside.
  • Ships to all 50 states, DC, Puerto Rico & the U.S. Virgin Islands; tracking emailed on every order.
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Quality & Testing

  • No third-party certificate has been published for this compound yet.
  • USA-based; dispatched from Phoenix, Arizona.
  • Supplied strictly for in-vitro laboratory research — not for human use.

Certificates are published for each lot we have tested — see the 14 published so far.

Research Applications

1GHRH receptor pharmacology in pituitary cell models
2Albumin bioconjugation and DPP-IV stability studies
3Comparative studies of DAC and no-DAC GRF(1-29) analogs

References & Citations

(1)
1

Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog.

Jetté L, Léger R, Thibaudeau K, et al.

Endocrinology (2005)PMID: 15817669 DOI

Research Use Only

This product is intended strictly for in-vitro research, educational, and laboratory use. Not for human consumption. The information provided is based on published research and does not constitute medical advice.